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J Cell Sci (2006) 119 (21): 4520–4530.
Published: 1 November 2006
... of attracting monocytes. Additionally, we showed that Nef-induced CCL2/MCP-1 expression depends on the myristoylation moiety of Nef and requires functional calmodulin. In summary, we suggest that Nef-induced CCL2/MCP-1 expression in astrocytes contributes to infiltration of monocytes into the brain, and thereby...
J Cell Sci (2005) 118 (11): 2495–2505.
Published: 1 June 2005
... that the NCS protein VILIP-1 influences the activity of the receptor guanylyl cyclase GC-B. In transfected cell lines, VILIP-1 performs a Ca 2+ -dependent membrane association, the reversible Ca 2+ -myristoyl switch of VILIP-1, which leads to an increase in natriuretic peptide-stimulated cGMP levels...
J Cell Sci (2004) 117 (6): 943–954.
Published: 22 February 2004
...Susanne Bolte; Spencer Brown; Béatrice Satiat-Jeunemaitre We report on the sub-cellular localisation and function of m-Rab mc , a N-myristoylated plant-specific Rab-GTPase previously characterised at the molecular level and also by structural analysis in Mesembryanthemum crystallinum . By confocal...
Includes: Supplementary data
J Cell Sci (2002) 115 (23): 4433–4445.
Published: 1 December 2002
... signal. When expressed in COS-7 cells, mutant hARL5(T35N), which is predicted to be GDP bound, was concentrated in nucleoli. The N-terminus of hARL5, like that of ARF, was myristoylated. Yeast two-hybrid screening and in vitro protein-interaction assays showed that hARL5(Q80L),predicted to be GTP bound...
Daijiro Konno, Ji-Ae Ko, Shinichi Usui, Kei Hori, Hisato Maruoka, Makoto Inui, Takashi Fujikado, Yasuo Tano, Tatsuo Suzuki, Koujiro Tohyama, Kenji Sobue
J Cell Sci (2002) 115 (23): 4695–4706.
Published: 1 December 2002
... product. PSD-Zip70 contains an N-myristoylation consensus sequence, a polybasic cluster in the N-terminal region and four leucine-zipper motifs in the C-terminal region. Light and electron microscopy showed that this protein was localized to the dendritic spines, especially in the PSD and the postsynaptic...
Inmaculada Navarro-Lérida, Alberto Álvarez-Barrientos, Francisco Gavilanes, Ignacio Rodriguez-Crespo
J Cell Sci (2002) 115 (15): 3119–3130.
Published: 1 August 2002
...Inmaculada Navarro-Lérida; Alberto Álvarez-Barrientos; Francisco Gavilanes; Ignacio Rodriguez-Crespo Using recursive PCR, we created an artificial protein sequence that consists of a consensus myristoylation motif (MGCTLS) followed by the triplet AGS repeated nine times and fused to the GFP...
J Cell Sci (2002) 115 (12): 2465–2473.
Published: 15 June 2002
...Sang Soo Kim; Jung Hwa Kim; Seung-Hye Lee; Sung Soo Chung; Ok-Sun Bang; Dongeun Park; Chin Ha Chung Myristoylated alanine-rich C kinase substrate (MARCKS) translocates from the cytosol to the plasma membrane while mononucleated myoblasts fuse to form multinucleated myotubes. Here, we show...
Heike B. Eberle, Ramon L. Serrano, Joachim Füllekrug, Andreas Schlosser, Wolf D. Lehmann, Friedrich Lottspeich, Dora Kaloyanova, Felix T. Wieland, J. Bernd Helms
J Cell Sci (2002) 115 (4): 827–838.
Published: 15 February 2002
... A. By mass spectrometry, GAPR-1 was shown to be myristoylated. Immunoprecipitation of GAPR- 1 from Golgi membranes resulted in the coimmunoprecipitation of caveolin-1, indicating a direct interaction between these two proteins. Myristoylation, together with protein-protein or electrostatic interactions...
J Cell Sci (1997) 110 (5): 673–679.
Published: 1 March 1997
...P. Zlatkine; B. Mehul; A. I. Magee ABSTRACT Several members of the Src family of protein tyrosine kinases have a N-terminal dual acylation motif which specifies their myristoylation and S-acylation. These lipid modifications are necessary for correct intracellular localisation to the plasma...
J Cell Sci (1993) 105 (3): 613–628.
Published: 1 July 1993
...Thérèse David-Pfeuty; Shubha Bagrodia; David Shalloway ABSTRACT Myristoylation of pp60 src is required for its membrane attachment and transforming activity. The mouse monoclonal antibody, mAb327, which recognizes both normal, myristoylated pp60 c-src and a nonmyristoylated mutant, pp60 c-src/myr...