... is crucial for muscle function. Myonuclei differ in transcriptional activity and protein accumulation, but how these differences among nuclei sharing a cytoplasm are achieved is unknown. Regulated nuclear import of proteins is one potential mechanism for regulating transcription spatially and temporally...

... © The Company of Biologists Limited 2005 2005 Skeletal muscle Myonuclei Inositol 1 4 5-trisphosphate receptors Nuclear envelope Transcription factors Gene expression Ionized calcium is a versatile second messenger that mediates a wide variety of biological processes in cells...