...) signaling, which modulates myofibroblast fate, extracellular matrix remodeling and fibrosis. However, the molecular determinants of MSC differentiation and survival remain poorly understood. During canonical Wnt signaling, T-cell factor/lymphoid enhancer factor (TCF/LEF) transcription factors regulate...

... CXCL10 gene repression in idiopathic pulmonary fibrosis . Am. J. Respir. Cell Mol. Biol.   58 , 449 - 460 . 10.1165/rcmb.2017-0286OC Darby , I. A. , Laverdet , B. , Bonte , F. and Desmouliere , A. ( 2014 ). Fibroblasts and myofibroblasts in wound healing . Clin. Cosmet...

...Ryan H. Cunnington; Josette M. Northcott; Saeid Ghavami; Krista L. Filomeno; Fahmida Jahan; Morvarid S. Kavosh; Jared J. L. Davies; Jeffrey T. Wigle; Ian M. C. Dixon ABSTRACT Cardiac fibrosis is linked to fibroblast-to-myofibroblast phenoconversion and proliferation but the mechanisms underlying...

...Matthew W. C. Chan; Pamma D. Arora; Peter Bozavikov; Christopher A. McCulloch During the development of pressure-induced cardiac hypertrophy, fibroblasts are activated to become myofibroblasts, which exhibit actin-cytoskeletal remodeling and express α-smooth muscle actin (SMA; encoded by ACTA2...

...Andrew Leask; Xu Shi-wen; Korsa Khan; Yunliang Chen; Alan Holmes; Mark Eastwood; Christopher P. Denton; Carol M. Black; David J. Abraham Cutaneous wound repair requires the de novo induction of a specialized form of fibroblast, the α-smooth muscle actin (α-SMA)-expressing myofibroblast, which...

... . * Author for correspondence (e-mail: furuya@med.nagoya-u.ac.jp ) 22 4 2005 © The Company of Biologists Limited 2005 2005 Subepithelial fibroblasts Mechanosensing Intestine ATP release P2Y Myofibroblasts Under the epithelium of the gastrointestinal tract, subepithelial...