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Keywords: Myofibrillogenesis
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Journal Articles
Journal Articles
J Cell Sci (2009) 122 (7): 947–956.
Published: 1 April 2009
..., and, given the phenotype of obscurin and TC10 disruption in striated muscle, we expect that some human skeletal myopathies arise from defects in obscuring-TC10 pathway. We recently demonstrated the role of TC10 in myofibrillogenesis in an ascidian model ( Coisy-Quivy et al., 2006 ). To explore its...
Includes: Supplementary data
Journal Articles
J Cell Sci (2006) 119 (20): 4322–4331.
Published: 15 October 2006
...-binding sites intact. ES cells were differentiated into cardiomyocytes, and myofibrillogenesis investigated by immunofluorescence microscopy. Surprisingly, deletion of one allele did not markedly affect differentiation into cardiomyocytes, suggesting that a single intact copy of the titin gene...
Journal Articles
Journal Articles
J Cell Sci (2004) 117 (9): 1795–1805.
Published: 1 April 2004
... genetic system with which to study myofibrillogenesis in vivo . We show in this paper that neither sarcomeric myosin nor actin are required for myoblast fusion or the subsequent morphogenesis of muscle fibres, i.e. fibre morphogenesis does not depend on myofibrillogenesis. However, fibre formation...
Journal Articles
J Cell Sci (2004) 117 (1): 105–114.
Published: 1 January 2004
... of Biologists Limited 2004 2004 Myofibrillogenesis Cardiomyocytes N-RAP Actin N-RAP is a ∼190 kDa actin binding LIM protein found in skeletal and cardiac muscle tissues ( Luo et al., 1997 ; Mohiddin et al., 2003 ). In addition to its N-terminal LIM domain, N-RAP contains 10 or 11 simple...
Journal Articles
J Cell Sci (2003) 116 (23): 4811–4819.
Published: 1 December 2003
... for initiating or regulating myofibrillogenesis. We used a gene-targeting approach in cultured myoblasts to truncate the titin gene so that the kinase domain and other domains downstream of the kinase were not expressed. We recovered cells in which one allele was targeted. We found that these cells expressed...
Journal Articles
Journal Articles
J Cell Sci (2000) 113 (8): 1405–1414.
Published: 15 April 2000
... and in the coordination of myofibrillogenesis. * Author for correspondence (e-mail: [email protected] ) 10 02 2000 21 03 2000 © 2000 by Company of Biologists 2000 Titin/connectin BHK-21C/13 cell Null mutation Myofibrillogenesis Myofibroblast Myosin assembly Titin (also...
Journal Articles
J Cell Sci (1999) 112 (22): 4101–4112.
Published: 15 November 1999
[email protected] ) * These three authors contributed equally to this report 25 08 1999 11 03 1999 © 1999 by Company of Biologists 1999 Myofibrillogenesis MYC-tagged s-α-actinin GFP-tagged T-cap Titin Nebulin α-Actin Much is known about how in cell free systems two...
Journal Articles
Journal Articles
Journal Articles
J Cell Sci (1995) 108 (2): 581–593.
Published: 1 February 1995
... binding protein actin myofibrillogenesis muscle cell phosphatidylinositol 4,5-bisphosphate (PIP 2 ) microinjection Multiple actin-regulatory proteins have been characterized as being profoundly involved in various cell functions by regulating the assembly and disassembly of actin (for review...
Journal Articles
J Cell Sci (1994) 107 (3): 377–386.
Published: 1 March 1994
... 23 08 1993 03 12 1993 © 1994 by Company of Biologists 1994 in situ hybridization costamere myofibrillogenesis intermediate filaments mRNA Costameres are ribs of protein that contain vinculin and lie between the cell membrane and the Z line in some skeletal muscles...
Journal Articles