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Keywords: Myoblasts
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Journal Articles
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Stem Cells
J Cell Sci (2020) 133 (12): jcs242297.
Published: 19 June 2020
... the expression and function of TCF7L2 (also known as TCF4), using several models of MSCs, including skeletal muscle fibro-adipogenic progenitors. We show that TCF/LEFs are differentially expressed and that TGF-β reduces the expression of TCF7L2 in MSCs but not in myoblasts. We also found that the ubiquitin...
Includes: Supplementary data
Journal Articles
J Cell Sci (2012) 125 (24): 6147–6156.
Published: 15 December 2012
... activity is associated with increased viability of human myoblasts. In addition to its detoxifying activity, aldehyde dehydrogenase can also catalyze the irreversible oxidation of vitamin A to retinoic acid; therefore, we examined whether retinoic acid is important for myoblast viability. We showed...
Includes: Supplementary data
Journal Articles
J Cell Sci (2012) 125 (5): 1309–1317.
Published: 1 March 2012
... © 2012. 2012 Slow-dividing cells Satellite cells Skeletal muscle Myoblasts Self-renewal Stemness Satellite cells are muscle tissue stem cells located between the basal lamina and plasma lemma of myofibres and play important roles in postnatal muscle growth, as well as adult muscle...
Includes: Supplementary data
Journal Articles
J Cell Sci (2011) 124 (22): 3835–3847.
Published: 15 November 2011
... myoblasts sensitized the cells to mitochondria-associated intrinsic apoptosis induced by cell confluence or serum starvation. Further investigation of this pathway revealed that M-cadherin-mediated signaling suppressed GSK-3β activation by enhancing the PI3K/AKT-dependent inhibitory phosphorylation of Ser9...
Includes: Supplementary data
Journal Articles
J Cell Sci (2007) 120 (22): 4050–4059.
Published: 15 November 2007
... on proliferation, migration and myogenic differentiation of mouse C2C12 myogenic progenitor/myoblast cells. In addition, we have characterized the signaling pathways employed by SDF1-CXCR4 to control myogenesis. We found that SDF1 stimulates proliferation and induces migration of C2C12 cells with a potency similar...
Includes: Supplementary data
Journal Articles
J Cell Sci (2006) 119 (17): 3561–3570.
Published: 1 September 2006
...Nathan T. Swailes; Melanie Colegrave; Peter J. Knight; Michelle Peckham The interaction of non-muscle myosins 2A and 2B with actin may drive changes in cell movement, shape and adhesion. To investigate this, we used cultured myoblasts as a model system. These cells characteristically change shape...
Includes: Multimedia, Supplementary data
Journal Articles
J Cell Sci (2005) 118 (1): 27–37.
Published: 1 January 2005
... and regenerating tibialis anterior muscle and in primary cultures of differentiating myoblasts in adult and newborn mice, respectively. Cxs 45 and 43, but not 40, were strongly expressed in normal muscle and their expression was upregulated during regeneration. Furthermore, the functional role of Cx43 during...
Journal Articles
J Cell Sci (2004) 117 (22): 5393–5404.
Published: 15 October 2004
...-mail: reuveni@u.washington.edu ) 27 7 2004 © The Company of Biologists Limited 2004 2004 Skeletal muscle satellite cells Mesenchymal stem cells Myoblasts Adipocytes Pax7 protein The growth and repair potential of adult skeletal muscle relies on a reservoir of myogenic precursors...
Journal Articles
J Cell Sci (2002) 115 (2): 355–366.
Published: 15 January 2002
... to this lectin results in 100% conversion of the cells. Conversion was assessed by the expression within the cells of the muscle-specific cytoskeletal protein desmin. We also investigate the effects of galectin-1 on cells of the C2C12 mouse myogenic cell line and on primary mouse myoblasts. Exposing both...
Journal Articles
J Cell Sci (2001) 114 (22): 4001–4011.
Published: 15 November 2001
... lamin speckles that associate with RNA splicing factor speckles in C2C12 myoblasts and myotubes. Lamin speckles were observed in dividing myoblasts but disappeared early during the course of differentiation in postmitotic myocytes, and were absent in myotubes and muscle fibers. However, no changes were...