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Keywords: Myoblast
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Journal Articles
In collection:
Cell Cycle , Stem Cells
J Cell Sci (2022) 135 (15): jcs259789.
Published: 5 August 2022
...Hardik P. Gala; Debarya Saha; Nisha Venugopal; Ajoy Aloysius; Gunjan Purohit; Jyotsna Dhawan ABSTRACT Adult stem cells persist in mammalian tissues by entering a state of reversible quiescence, referred to as G 0 , which is associated with low levels of transcription. Using cultured myoblasts...
Includes: Supplementary data
Journal Articles
J Cell Sci (2017) 130 (18): 3083–3093.
Published: 15 September 2017
...Julie Perroud; Laurent Bernheim; Maud Frieden; Stephane Koenig ABSTRACT Ca 2+ signaling plays a key role during human myoblast differentiation. Among Ca 2+ -sensitive pathways, calcineurin is essential for myoblast differentiation and muscle regeneration. Nuclear factor of activated T-cell (NFAT...
Includes: Supplementary data
Journal Articles
Journal Articles
J Cell Sci (2010) 123 (18): 3052–3060.
Published: 15 September 2010
... ) 1 6 2010 © 2010. 2010 Fusion Myoblast Myocyte CXCR4 SDF-1α Regeneration Skeletal muscle degeneration can occur as a result of disease or injury; however, this tissue has an extensive ability to regenerate. Adult regenerative myogenesis is dependent on progenitor cells...
Includes: Supplementary data
Journal Articles
J Cell Sci (2010) 123 (14): 2413–2422.
Published: 15 July 2010
..., during which it mediates myoblast fusion. We isolated both damaged and intact myofibers from a mouse model of muscular dystrophy using laser-capture microdissection and found that the levels of myoferlin mRNA and protein were increased in damaged myofibers. To better define the components of the muscle...
Includes: Supplementary data
Journal Articles
J Cell Sci (2009) 122 (24): 4427–4438.
Published: 15 December 2009
... ) ‡ These authors contributed equally 20 9 2009 © The Company of Biologists Limited 2009 2009 Satellite cell Myoblast Presenilin-1 Id1 Pax7 MyoD γ-secretase Self-renewal Skeletal muscle Myogenic differentiation Stem cell Cell fate choice Muscle satellite cells are myogenic...
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Journal Articles
J Cell Sci (2008) 121 (23): 3951–3959.
Published: 1 December 2008
...Magali Louis; Nadège Zanou; Monique Van Schoor; Philippe Gailly Myoblast migration is a key step in myogenesis and regeneration. It allows myoblast alignment and their fusion into myotubes. The process has been shown to involve m-calpain or μ-calpain, two Ca 2+ -dependent cysteine proteases. Here...
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J Cell Sci (2001) 114 (11): 2187–2198.
Published: 1 June 2001
..., the involvement of tyrosine phosphatases in this process is unknown. SHP-2 is an SH2 domain-containing tyrosine phosphatase, which positively regulates growth and differentiation. We show that in C2C12 myoblasts, SHP-2 becomes upregulated early on during myogenesis and associates with a 120 kDa tyrosyl...
Journal Articles
J Cell Sci (2000) 113 (24): 4427–4433.
Published: 15 December 2000
... the receptor. Activators of PAR-2 include trypsin and mast cell tryptase. Skeletal myoblasts are known to express PAR-1, a thrombin receptor. The current study was undertaken to determine whether myoblasts express PAR-2. Primary neonatal rat and mouse skeletal myoblast cultures were shown to express PAR-2...
Journal Articles
J Cell Sci (2000) 113 (15): 2695–2703.
Published: 1 August 2000
... load, there is little knowledge of how muscle cells are initially determined in the early embryo. In the zebrafish, fibres of the slow twitch class arise from precociously specified myoblasts that lie close to the midline whereas the remainder of the myotome differentiates as fast myosin expressing...
Journal Articles
Journal Articles
J Cell Sci (1999) 112 (10): 1425–1436.
Published: 15 May 1999
...Hyun J. Ra; Catherine Picart; Huisheng Feng; H. Lee Sweeney; Dennis E. Discher ABSTRACT To quantitatively elucidate attributes of myocyte-matrix adhesion, muscle cells were controllably peeled from narrow strips of collagen-coated glass. Initial growth of primary quail myoblasts on collagen strips...
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Journal Articles
J Cell Sci (1998) 111 (22): 3287–3297.
Published: 15 November 1998
...A. Irintchev; J. D. Rosenblatt; M. J. Cullen; M. Zweyer; A. Wernig ABSTRACT We investigated the potential of cultured myoblasts to generate skeletal muscle in an ectopic site. Myoblasts from a clonal cell line or from expanded primary cultures were injected under the skin of the lumbar region...
Journal Articles
J Cell Sci (1996) 109 (13): 3139–3150.
Published: 15 December 1996
... the role of α7 integrin in mediating myoblast adhesion and motility on different laminin isoforms. Mouse C2C12 and MM14 myoblast cell lines were found by flow cytometry and immunoprecipitation to express high levels of the α7 integrin. Overall expression of α7 increased as the C2C12 myoblasts...