...Valeria Runfola; Soji Sebastian; F. Jeffrey Dilworth; Davide Gabellini ABSTRACT Among the Mef2 family of transcription factors, Mef2D is unique in that it undergoes tissue-specific splicing to generate an isoform that is essential for muscle differentiation. However, the mechanisms mediating...

... processing factors in the maintenance of muscle integrity. We speculate that mute regulates terminal muscle differentiation possibly through heterochromatic reorganisation. * Author for correspondence ( [email protected] ) ‡ Present address: Ministry of Education, 248922, Singapore...

... during muscle differentiation. We have recently demonstrated that the expression of RPB3 is regulated during muscle differentiation and that, inside RNA polymerase II (RNAP II), it is directly involved in contacting regulatory proteins such as the myogenic transcription factor Myogenin and activating...

... have two genes that are located on different chromosomes, encode distinct UNC-45-like protein isoforms, and are expressed either in multiple tissues or only in cardiac and skeletal muscles. Their expression is regulated during muscle differentiation in vitro, with the striated muscle isoform mRNA...

... ) 17 10 2001 © The Company of Biologists Limited 2002 2002 Dermal fibroblast Galectin-1 Myogenic conversion Muscle differentiation Myoblasts Recent work in our laboratory has identified a factor that is capable of converting murine dermal fibroblasts to muscle cells ( Goldring...

... and Olson, 1998 ). Although it is established that MEF2 factors play a critical role in muscle differentiation and development, subsequent studies have demonstrated that, with few exceptions, they are expressed ubiquitously and might have additional functions apart from their involvement in myogenesis...

...Bh. Muralikrishna; Jyotsna Dhawan; Nandini Rangaraj; Veena K. Parnaik Intranuclear lamin foci or speckles have been observed in various cell types. In order to explore the possibility of changes in internal lamin organization during muscle differentiation, we have examined the appearance of A-type...

... on the onset of muscle differentiation in the absence of a correct cell cycle arrest. Here we report that polyomavirus large T increases the levels and activity of p53, but these alterations are not involved in the apoptotic mechanism. Apoptosis in polyomavirus large T-expressing myoblasts is not prevented...

... cell adhesion molecule skeletal muscle muscle differentiation Embryonic cells in somites are first committed to become muscle precursor cells. These precursors migrate to invade the future muscle territories while they are continuing to divide. Then, during the process of terminal commitment...

... ). Thism vivo development is faithfully reproduced in cultures of embryonic myogenic cells in vitro ( Konigsberg, 1960 , 1963 , 1965 , 1982 ; Yaffe, 1969 ; Bischoff and Holtzer, 1969 ). skeletal muscle myoblasts muscle differentiation myofibrillogenesis. © 1990 by Company...

... in all cell types (myoblasts, myotubes and fibroblasts) and there are no major changes during muscle differentiation. From known changes in ribosomal RNA metabolism during myogenesis and after actinomycin D treatment, we suggest that the 37 000 M r protein is involved in some post-transcriptional aspect...