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Keywords: Multivesicular bodies
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Journal Articles
Journal Articles
J Cell Sci (2011) 124 (21): 3537–3544.
Published: 1 November 2011
... of GSK3 as pseudo-substrates, thus directly blocking its activity against β-catenin. A distinct cell-biological model was proposed more recently: Wnt proteins induce the uptake of GSK3 into multivesicular bodies (MVBs), an event that sequesters the enzyme away from newly synthesised β-catenin substrate...
Journal Articles
J Cell Sci (2007) 120 (1): 191–199.
Published: 1 January 2007
.... Loss of phosphorylation reduces internalisation of FasL into multivesicular bodies. FasL is also directly mono-ubiquitylated at lysines flanking the PRD and mutation of these lysines reduces MVB localisation of FasL. Phosphorylation is not required for ubiquitylation because FasL lacking all tyrosines...
Journal Articles
Journal Articles