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Helena Pinheiro, Mafalda Ramos Pimentel, Catarina Sequeira, Luís Manuel Oliveira, Anna Pezzarossa, William Roman, Edgar R. Gomes
J Cell Sci (2021) 134 (14): jcs256388.
Published: 23 July 2021
... 2021 Summary: Skeletal muscle cells are multinucleated fibers that express some of the biggest mammalian proteins. We report that mRNA length contributes to mRNA distribution and that microtubules are involved in mRNA spreading. Compartmentalization mRNA distribution mRNA size mRNA...
Includes: Supplementary data
Marie Pereira, Enrico Petretto, Siamon Gordon, J. H. Duncan Bassett, Graham R. Williams, Jacques Behmoaras
J Cell Sci (2018) 131 (11): jcs216267.
Published: 05 June 2018
...Marie Pereira; Enrico Petretto; Siamon Gordon; J. H. Duncan Bassett; Graham R. Williams; Jacques Behmoaras ABSTRACT Macrophage cell fusion and multinucleation are fundamental processes in the formation of multinucleated giant cells (MGCs) in chronic inflammatory disease and osteoclasts...
Akiyoshi Hoshino, Satoshi Ueha, Sanshiro Hanada, Toshio Imai, Masako Ito, Kenji Yamamoto, Kouji Matsushima, Akira Yamaguchi, Tadahiro Iimura
J Cell Sci (2013) 126 (4): 1032–1045.
Published: 15 February 2013
... showed positive signals in mononuclear osteoclast progenitors and multinucleated osteoclastic cells ( Fig. 6A , in red). Fig. 6B summarizes the expression levels of osteoclast-related markers as determined by RT-PCR. The expression levels of Rank , Nfat-c1 , Trap5b , Cathepsin K, Integrin alphaV...
Jiro Takito, Masanori Nakamura, Masaki Yoda, Takahide Tohmonda, Shinichi Uchikawa, Keisuke Horiuchi, Yoshiaki Toyama, Kazuhiro Chiba
J Cell Sci (2012) 125 (3): 662–672.
Published: 01 February 2012
...Jiro Takito; Masanori Nakamura; Masaki Yoda; Takahide Tohmonda; Shinichi Uchikawa; Keisuke Horiuchi; Yoshiaki Toyama; Kazuhiro Chiba Multinucleated osteoclasts are responsible for bone resorption. Hypermultinucleated osteoclasts are often observed in some bone-related diseases such as Paget's...
Includes: Multimedia, Supplementary data