1-20 of 40
Keywords: Mouse
Close
Follow your search
Access your saved searches in your account

Would you like to receive an alert when new items match your search?
Close Modal
Sort by
Journal Articles
J Cell Sci jcs.258798.
Published: 20 January 2022
... transcription and spatial organization in embryos, we focused on the ribosomal genes, that are first silent and begin to transcribe during the 2-cell stage in the mouse. We demonstrated that ribosomal sequences and early unprocessed rRNAs are spatially organized in a very peculiar manner from the 2-cell...
Journal Articles
In collection:
Cytoskeleton
J Cell Sci (2021) 134 (24): jcs259237.
Published: 20 December 2021
...Anne Bourdais; Benoit Dehapiot; Guillaume Halet ABSTRACT How multiple actin networks coexist in a common cytoplasm while competing for a shared pool of monomers is still an ongoing question. This is exemplified by meiotic maturation in the mouse oocyte, which relies on the dynamic remodeling...
Includes: Supplementary data
Journal Articles
J Cell Sci (2022) 135 (5): jcs258364.
Published: 11 May 2021
... of the phosphoinositide 5′-phosphatase gene Inpp5e , mutation of which is causative of Joubert syndrome, in terminally developed mouse olfactory sensory neurons (OSNs), leads to a dramatic remodeling of ciliary phospholipids that is accompanied by marked elongation of cilia. Phosphatidylinositol (4,5)-bisphosphate [PI...
Includes: Supplementary data
Journal Articles
J Cell Sci (2019) 132 (14): jcs230565.
Published: 26 July 2019
... of motility and phosphotyrosine inhibition produced by MK571. These results were supported using spermatozoa from CatSper Ca 2+ channel knockout mice. Taken together, these results suggest that cAMP efflux via MRP4 plays an essential role in mouse sperm capacitation. This article has an associated First...
Includes: Supplementary data
Journal Articles
J Cell Sci (2019) 132 (2): jcs224097.
Published: 16 January 2019
... that a substantial amount of Cx30-A88V co-localized with GM130, a marker for the Golgi apparatus ( Fig. S1 ). Since the Cx30-A88V mutant was found to be toxic in vitro , it was somewhat surprising that a mouse model expressing the mutant did not exhibit pronounced hearing loss ( Bosen et al., 2014...
Includes: Supplementary data
Journal Articles
J Cell Sci (2017) 130 (7): 1321–1332.
Published: 01 April 2017
...Ryo Iwamoto; Naoki Mine; Hiroto Mizushima; Eisuke Mekada ABSTRACT Heparin-binding EGF-like growth factor (HB-EGF) plays an indispensable role in suppression of cell proliferation during mouse valvulogenesis. However, ligands of the EGF receptor (EGFR/ErbB1), including HB-EGF, are generally...
Includes: Supplementary data
Journal Articles
J Cell Sci (2015) 128 (14): 2468–2481.
Published: 15 July 2015
...Sarah Escuin; Bertrand Vernay; Dawn Savery; Christine B. Gurniak; Walter Witke; Nicholas D. E. Greene; Andrew J. Copp ABSTRACT The cytoskeleton is widely considered essential for neurulation, yet the mouse spinal neural tube can close despite genetic and non-genetic disruption of the cytoskeleton...
Includes: Supplementary data
Journal Articles
J Cell Sci (2014) 127 (3): 641–652.
Published: 01 February 2014
... from brain homogenate at embryonic day E14 ( Fig. 3B ) indicating that TNR and β1 integrin are associated during mouse brain development. * Author for correspondence ( schachner@zmnh.uni-hamburg.de ) Competing interests The authors declare no competing financial interests. 1 07...
Includes: Supplementary data
Journal Articles
J Cell Sci (2013) 126 (22): 5111–5115.
Published: 15 November 2013
.... Using immunohistochemistry, we found the glycoprotein tenascin-C in the fibrous capsule of mouse whisker follicles, along the glassy membrane and in the trabecular region surrounding keratin-15-negative, CD34-positive stem cells. The related glycoprotein tenascin-W is found in the CD34-positive stem...
Journal Articles
J Cell Sci (2013) 126 (18): 4239–4252.
Published: 15 September 2013
... (SMC2/4) and sister-chromatid cohesion (SMC1/3). The SMC5/6 complex has been implicated in chromosome replication, DNA repair and chromosome segregation in somatic cells, but its possible functions during mammalian meiosis are unknown. Here, we show in mouse spermatocytes that SMC5 and SMC6 are located...
Includes: Supplementary data
Journal Articles
J Cell Sci (2013) 126 (7): 1672–1681.
Published: 01 April 2013
... at fertilization, which takes the form of a single (e.g. Xenopus ) or multiple (e.g. mouse) Ca 2+ spikes depending on the species. Store-operated Ca 2+ entry (SOCE) is the predominant Ca 2+ influx pathway in vertebrate oocytes, and in Xenopus SOCE completely inactivates during meiosis. Here, we show that SOCE...
Includes: Supplementary data
Journal Articles
J Cell Sci (2012) 125 (21): 5005–5014.
Published: 01 November 2012
..., and the mucosal response to acute injury in the duodenum. * Author for correspondence ( sandra.citi@unige.ch ) 30 7 2012 © 2012. Published by The Company of Biologists Ltd 2012 Cingulin Claudin-2 Mouse Tight junctions, ZO-1, Occludin, RhoA Vertebrate epithelial cells display...
Includes: Supplementary data
Journal Articles
J Cell Sci (2011) 124 (14): 2357–2366.
Published: 15 July 2011
... in SSCs, thereby contributing to SSC fate control and their directional localization in the seminiferous epithelium. Because Wnt5a-knockout mice die perinatally ( Yamaguchi et al., 1999 ), in vivo analyses of such Wnt5a actions will require a conditional-knockout mouse model, and our study provides...
Includes: Supplementary data
Journal Articles
J Cell Sci (2010) 123 (3): 331–339.
Published: 01 February 2010
... to haploid gene expression, in mammalian round spermatids. However, little is known about functions and fate of the CB at later steps of spermatogenesis, when elongating spermatids undergo chromatin compaction and transcriptional silencing. In mouse elongating spermatids, we detected accumulation...
Includes: Supplementary data
Journal Articles
J Cell Sci (2009) 122 (17): 3070–3082.
Published: 01 September 2009
... investigated the function of the primary cilium in regulating hedgehog signaling and early cardiogenesis. We report that the pluripotent P19.CL6 mouse stem cell line, which can differentiate into beating cardiomyocytes, forms primary cilia that contain essential components of the hedgehog pathway, including...
Includes: Supplementary data
Journal Articles
J Cell Sci (2009) 122 (12): 2149–2159.
Published: 15 June 2009
... The Company of Biologists Limited 2009 2009 CDK2 Chromosome synapsis Meiosis Meiotic recombination Mouse Sex body The progression through the various phases of the cell cycle and subsequent cell divisions in eukaryotic cells is driven by a group of serine/threonine protein kinases, termed...
Includes: Multimedia, Supplementary data
Journal Articles
J Cell Sci (2009) 122 (5): 735–744.
Published: 01 March 2009
... proteins 4.1G and 4.1N were previously suggested to act jointly in binding and regulating synaptic trafficking of the AMPA receptor subunits GluR1 and GluR4. To determine the functions of 4.1G and 4.1N in vivo, we generated a mutant mouse line that lacks 4.1G entirely and expresses 4.1N at 22% of wild-type...
Includes: Supplementary data
Journal Articles
J Cell Sci (2009) 122 (4): 453–459.
Published: 15 February 2009
... al., 1977 ). Hybridomas were screened by adding hybridoma supernatants at a dilution of 50% v/v to the macrophage fusion assay. Clones MF2, 3 and 4 were re-cloned twice. Antibodies were purified from hybridoma supernatants using Gamma Bind Plus Sepharose beads (GE Healthcare). Mouse osteoclast...
Journal Articles
J Cell Sci (2008) 121 (19): 3233–3242.
Published: 01 October 2008
... and killed either 24 hours or 8 days later. Testes were fixed in Bouin's fluid for 24 hours and then embedded in paraffin. BrdU incorporation was detected by using an anti-BrdU mouse monoclonal antibody (diluted 1:100; Roche) and indirect immunofluorescence labelling. For detection of apoptotic cells (TUNEL...
Includes: Supplementary data
Journal Articles
J Cell Sci (2008) 121 (10): 1758–1769.
Published: 15 May 2008
...Denggao Yao; Claire L. Alexander; Jean A. Quinn; Weng-Chyn Chan; Hong Wu; David A. Greenhalgh To investigate gene synergism in multistage skin carcinogenesis, the RU486-inducible cre/lox system was employed to ablate Pten function ( K14.cre/ Δ 5Pten flx ) in mouse epidermis expressing activated Fos...
Includes: Supplementary data