... motile cilia-independent function in normal epithelium. This isoform has previously been shown to be expressed in human testis extracts and HBEC lysates by immunoblotting, but was not fully characterized until now ( Lin et al., 2001 ; Neesse et al., 2007 ; Knowles et al., 2013 ). The mouse homolog...

...Yu-Jie Wu; Yue Liu; Yan-Qin Hu; Li Wang; Fu-Rong Bai; Chen Xu; Jing-Wen Wu ABSTRACT Multiciliated cells (MCCs) are terminally differentiated postmitotic cells that possess hundreds of motile cilia on their apical surface. Defects in cilia formation are associated with ciliopathies that affect many...

... primary cilia (cumulus), as well as motile cilia and flagella (ependymal cells and spermatids). The ciliary pocket shares striking morphological and functional similarities with the flagellar pocket of Trypanosomatids, a trafficking-specialised membrane domain at the base of the flagellum. Our data...