1-20 of 64
Keywords: Morphogenesis
Close
Follow your search
Access your saved searches in your account

Would you like to receive an alert when new items match your search?
Close Modal
Sort by
Journal Articles
J Cell Sci (2022) 135 (21): jcs259208.
Published: 3 November 2022
... cells of plants and fungi as case study models, we review recent progress on CW mechanosensation and mechanical regulation, and their implications for the control of cell growth, morphogenesis and survival. * These authors contributed equally to this work ‡ Authors for correspondence...
Journal Articles
In collection:
Adhesion
J Cell Sci (2022) 135 (9): jcs259579.
Published: 6 May 2022
... adhesion in development and evolution. Inter-tissue adhesion can couple the motion of adjacent tissues, be the source of mechanical resistance that constrains morphogenesis, and transmit tension required for normal development. Tissue–tissue adhesion can also create mechanical instability that leads...
Journal Articles
J Cell Sci (2022) 135 (7): jcs259628.
Published: 7 April 2022
...Adrian Molière; Katharina B. Beer; Ann M. Wehman ABSTRACT Dopey family proteins play crucial roles in diverse processes from morphogenesis to neural function and are conserved from yeast to mammals. Understanding the mechanisms behind these critical functions could have major clinical significance...
Journal Articles
In collection:
Adhesion
J Cell Sci (2019) 132 (22): jcs229286.
Published: 21 November 2019
... dynamically remodel in response to physiological forces that challenge epithelial barrier function, such as cell shape changes (e.g. during cell division) or tissue stretching (e.g. during developmental morphogenesis). In this Review, we first introduce a framework to think about TJ remodeling across multiple...
Includes: Supplementary data
Journal Articles
J Cell Sci (2019) 132 (15): jcs228338.
Published: 7 August 2019
...Anna T. Bajur; K. Venkatesan Iyer; Elisabeth Knust ABSTRACT During morphogenesis, epithelia undergo dynamic rearrangements, which requires continuous remodelling of junctions and cell shape, but at the same time mechanisms preserving cell polarity and tissue integrity. Apico-basal polarity is key...
Includes: Supplementary data
Journal Articles
J Cell Sci (2019) 132 (7): jcs224063.
Published: 3 April 2019
... of cytohesin localization. Mechanotransduction Tension Morphogenesis Ajuba Mechanical forces experienced by cells can influence the shapes of individual cells, and the structures of tissues to which they contribute ( Heer and Martin, 2017 ). Additionally, through mechanotransduction, forces...
Includes: Supplementary data
Journal Articles
In collection:
Adhesion
J Cell Sci (2018) 131 (24): jcs225144.
Published: 18 December 2018
... domain of Talin allowing its recruitment to integrins at the plasma membrane. This process appears to be strictly required for integrin-mediated adhesion in Drosophila . Cell adhesion Drosophila Morphogenesis ECM Integrin Talin Rap1 The assembly and maintenance of tissue...
Includes: Supplementary data
Journal Articles
In collection:
Mechanobiology
J Cell Sci (2018) 131 (8): jcs210476.
Published: 23 April 2018
... the expression of frizzled-1, thus promoting signaling and proliferation downstream of Wnt3a in mammary epithelial cells. Mechanosensing Morphogenesis Morphodynamics Mechanotransduction Compliance The Wnt/β-catenin signaling pathway controls a variety of cellular behaviors including adhesion...
Includes: Supplementary data
Journal Articles
J Cell Sci (2017) 130 (19): 3261–3271.
Published: 1 October 2017
... glycoprotein SCUBE2 from humans . Biochem. J.   422 , 119 - 128 . 10.1042/BJ20090341 Vadon-Le Goff , S. , Hulmes , D. J. and Moali , C. ( 2015 ). BMP-1/tolloid-like proteinases synchronize matrix assembly with growth factor activation to promote morphogenesis and tissue remodeling...
Includes: Supplementary data
Journal Articles
J Cell Sci (2017) 130 (1): 243–259.
Published: 1 January 2017
... of an epithelium contributes to epithelial homeostasis and organogenesis. In fact, many cell lines now known to misorient mitotic spindles during 3D morphogenesis were initially characterized as polarizing slowly, a phenotype that we also observed in ZO-1-deficient monolayers ( Jaffe et al., 2008 ; Martín...
Includes: Supplementary data
Journal Articles
In collection:
Mechanobiology
J Cell Sci (2016) 129 (24): 4496–4508.
Published: 15 December 2016
...Jaime Jurado; Joaquín de Navascués; Nicole Gorfinkiel ABSTRACT We have investigated how cell contractility and adhesion are functionally integrated during epithelial morphogenesis. To this end, we have analysed the role of α -Catenin , a key molecule linking E-Cadherin-based adhesion...
Includes: Supplementary data
Journal Articles
J Cell Sci (2015) 128 (21): 3961–3976.
Published: 1 November 2015
... responses in adults. In this paper, we have investigated the contribution of the axis to the regulation of epithelial morphogenesis, using 3D organotypic cultures of MCF10A cells as a model. We have demonstrated that MEF2 transcriptional activity is upregulated during acini formation, which coincides...
Includes: Supplementary data
Journal Articles
J Cell Sci (2015) 128 (16): 3117–3130.
Published: 15 August 2015
.... Summary:   Trypanosoma brucei FLAM3 is a flagellar FAZ protein. Its depletion leads to a reduction in FAZ length, which has different consequences depending on the life cycle stage of the parasite. Trypanosomes Morphogenesis Flagellum attachment zone Trypanosoma brucei is a unicellular...
Includes: Supplementary data
Journal Articles
J Cell Sci (2015) 128 (8): 1580–1594.
Published: 15 April 2015
... at the proximal end of the FAZ. This contrasts with the flagellum, which is assembled at its distal end; hence, these two interconnected cytoskeletal structures have distinct spatially separated assembly sites. This challenging result has many implications for understanding the process of cell morphogenesis...
Includes: Supplementary data
Journal Articles
J Cell Sci (2014) 127 (20): 4396–4408.
Published: 15 October 2014
... ). Targeting of CFTR protein is linked to the polarization of human pancreatic duct cells in culture.   Eur. J. Cell Biol.   76 , 220 – 227 . 10.1016/S0171-9335(98)80037-X Joseph   A. , Yao   H. , Hinton   B. T. ( 2009 ). Development and morphogenesis of the Wolffian/epididymal duct, more...
Includes: Supplementary data
Journal Articles
J Cell Sci (2014) 127 (11): 2507–2517.
Published: 1 June 2014
... in normal physiology and to coordinate tension during morphogenesis. Though much is known about the biological mechanisms underlying junction formation, little is known about how tissue-scale mechanical properties are established. Here, we use deep atomic force microscopy (AFM) indentation to measure...
Includes: Supplementary data
Journal Articles
J Cell Sci (2014) 127 (11): 2542–2553.
Published: 1 June 2014
... Epiboly Cell intercalation Xenopus Lfc Myosin II Rho GTPases Morphogenesis Author contributions K.I., O.O. and S.S. designed the experiments, analyzed the data and wrote the manuscript. K. I. and O. O. performed the experiments. Funding This research was supported...
Includes: Supplementary data
Journal Articles
J Cell Sci (2014) 127 (1): 204–215.
Published: 1 January 2014
... flagellar localization matches closely, but not exactly, that of the paraflagellar rod, an extra-axonemal structure present in the flagellum. Knockdown of FLA1 or FLAM3 triggers similar defects in motility and morphogenesis, characterized by the assembly of a drastically reduced FAZ filament. FLAM3 remains...
Includes: Supplementary data
Journal Articles
J Cell Sci (2013) 126 (10): 2157–2163.
Published: 15 May 2013
...Annalisa Letizia; Sara Ricardo; Bernard Moussian; Nicolás Martín; Marta Llimargas Summary Regulated cell shape changes in epithelial cells, which contribute to most organs and tissues, are at the basis of morphogenesis. Crumbs (Crb) is an essential apical determinant controlling epithelial...
Includes: Supplementary data
Journal Articles
J Cell Sci (2012) 125 (23): 5781–5789.
Published: 1 December 2012
..., is essential for the control of morphogenesis. This defines a new paradigm, in which chemistry regulates growth. In summary, lack of linkages between the chitin ring and β(1-3)glucan at the mother – bud neck lead to neck growth and consequent widening. For the second prediction, methodologies...
Includes: Supplementary data