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Keywords: Moesin
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Journal Articles
Journal Articles
J Cell Sci (2019) 132 (15): jcs228338.
Published: 7 August 2019
...-1-1/ Summary: The dynamics of the evolutionarily conserved polarity regulator Crumbs at the plasma membrane is important for modulating junctional stability and tension during embryonic development of Drosophila . Apical Moesin β H -spectrin FERM protein FRAP Morphogenesis...
Includes: Supplementary data
Journal Articles
J Cell Sci (2016) 129 (13): 2548–2558.
Published: 1 July 2016
... form of the ERM protein moesin precludes the Ano1-dependent increase in membrane area. Furthermore, both full-length and the truncated dominant-negative forms of moesin co-localize with Ano1 to the microvilli, and the two proteins co-immunoprecipitate. The Ano1–moesin interaction limits Ano1 lateral...
Includes: Supplementary data
Journal Articles
J Cell Sci (2014) 127 (15): 3199–3204.
Published: 1 August 2014
...Andrea I. McClatchey ABSTRACT The cell cortex is a dynamic and heterogeneous structure that governs cell identity and behavior. The ERM proteins (ezrin, radixin and moesin) are major architects of the cell cortex, and they link plasma membrane phospholipids and proteins to the underlying cortical...
Includes: Supplementary data
Journal Articles
J Cell Sci (2014) 127 (5): 954–966.
Published: 1 March 2014
... of plasma membrane PtdIns4 P and PtdIns(4,5) P 2 and is crucial for actin organization, membrane trafficking and cell polarity. Female germ cells mutant for PI4KIIIα exhibit defects in cortical integrity associated with failure to recruit the cytoskeletal-membrane crosslinker Moesin and the exocyst subunit...
Includes: Supplementary data
Journal Articles
J Cell Sci (2013) 126 (24): 5670–5680.
Published: 15 December 2013
.... In addition, SrcY527F was less able to induce podosome rosettes in JNK1-null or JNK2-null mouse embryo fibroblasts than in wild-type counterparts. The kinase activity of JNK was essential for promoting podosome rosette formation but not for its localization to podosome rosettes. Moesin, a member of the ERM...
Includes: Supplementary data
Journal Articles
J Cell Sci (2013) 126 (5): 1247–1259.
Published: 1 March 2013
... inhibition of PLC. Severe retinal degeneration was also induced in the dark in otherwise wild-type flies by overexpression of a bacterial PtdIns P n phosphatase (SigD) to deplete PtdIns(4,5) P 2 . In degenerating trp photoreceptors, phosphorylated Moesin, a PtdIns(4,5) P 2 -regulated membrane–cytoskeleton...
Includes: Supplementary data
Journal Articles
Journal Articles
J Cell Sci (2009) 122 (19): 3492–3501.
Published: 1 October 2009
... transition from fluid to adhesive conditions involves an early polarization event and major rearrangements of the submembrane cytoskeleton that remain poorly understood. As regulation of cortical actin-membrane binding might be important in this process, we investigated the role of ezrin and moesin, which...
Includes: Multimedia, Supplementary data
Journal Articles
J Cell Sci (2007) 120 (5): 723–730.
Published: 1 March 2007
..., while actin-binding proteins such as ezrin and moesin direct binding of signaling molecules to actin filaments within the distal pole complex. Upon encountering an antigen-presenting cell (APC), a T cell undergoes dramatic structural changes. Migration ceases, the uropod retracts, and the leading edge...
Journal Articles
Journal Articles
J Cell Sci (2003) 116 (24): 4985–4995.
Published: 15 December 2003
...), usually together with moesin, spectrin(s) and plectin. In sections through lens fiber tissue, the short sides of the lens fiber hexagons appear to be enriched in the cadherin-based complexes, whereas the EPPD complexes also occur on the long sides. Moreover, high resolution double-label fluorescence...
Journal Articles
J Cell Sci (2002) 115 (6): 1221–1229.
Published: 15 March 2002
..., and the actin-binding domain of moesin fused to cyan fluorescent protein (cfp-Moe) to stain actin. Actin filament bundles were clearly seen in the protruding lamellae of the cells. FN matrix assembly appeared to be initiated as small spots of FN at the ends of actin filament bundles. The spots then elongated...
Includes: Multimedia, Supplementary data
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J Cell Sci (1994) 107 (9): 2509–2521.
Published: 1 September 1994
..., 77 and 72 kDa by overlay assay. The 80 kDa protein was identified as ezrin and the 77 and 72 kDa proteins as gastric forms of proteins structurally related to ezrin, such as radixin and moesin. In insect cells infected with a recombinant baculovirus, one-third of over-expressed ezrin accumulated...
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Journal Articles
Journal Articles