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Keywords: Mitochondrial fusion
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Journal Articles
J Cell Sci (2017) 130 (4): 671–681.
Published: 15 February 2017
.... ( 2015 ). Neuronal hypoxia disrupts mitochondrial fusion . Neuroscience   301 , 71 - 78 . 10.1016/j.neuroscience.2015.05.078 Saxton , W. M. and Hollenbeck , P. J. ( 2012 ). The axonal transport of mitochondria . J. Cell Sci.   125 , 2095 - 2104 . 10.1242/jcs.053850...
Journal Articles
J Cell Sci (2016) 129 (12): 2297–2306.
Published: 15 June 2016
... by the inner-membrane peptidases YME1L (also known as YME1L1) and OMA1. Long, membrane-bound forms of OPA1 are required for mitochondrial fusion, but their processing to short, soluble forms limits fusion and can facilitate mitochondrial fission. Excessive OPA1 processing by the stress-activated protease OMA1...
Journal Articles
J Cell Sci (2014) 127 (22): 4954–4963.
Published: 15 November 2014
.... This interaction leads to MFN1 deacetylation and activation, promoting mitochondrial fusion. Deficiency in HDAC6 or MFN1 prevents mitochondrial fusion induced by glucose deprivation. Unexpectedly, failure to undergo fusion does not acutely affect mitochondrial adaptive energy production; instead, it causes...
Includes: Supplementary data
Journal Articles
J Cell Sci (2014) 127 (1): 191–203.
Published: 01 January 2014
...Mamta Rai; Prasanna Katti; Upendra Nongthomba ABSTRACT Mitochondrial biogenesis and morphological changes are associated with tissue-specific functional demand, but the factors and pathways that regulate these processes have not been completely identified. A lack of mitochondrial fusion has been...
Includes: Supplementary data
Journal Articles
J Cell Sci (2013) 126 (23): 5369–5376.
Published: 01 December 2013
... of proteins involved in mitochondrial fusion and fission as regulators of Fog signaling. Pro-fission factors were found to function as enhancers of signaling, whereas pro-fusion factors were found to have the opposite effect. Consistent with this, activation of Fog signaling resulted in mitochondrial...
Includes: Supplementary data
Journal Articles
J Cell Sci (2013) 126 (10): 2187–2197.
Published: 15 May 2013
...Michal Cagalinec; Dzhamilja Safiulina; Mailis Liiv; Joanna Liiv; Vinay Choubey; Przemyslaw Wareski; Vladimir Veksler; Allen Kaasik Summary Mitochondrial fusion–fission dynamics play a crucial role in many important cell processes. These dynamics control mitochondrial morphology, which in turn...
Includes: Supplementary data
Journal Articles
J Cell Sci (2009) 122 (14): 2402–2412.
Published: 15 July 2009
... of mitochondrial DNA. To address the mode of action of Lga2, we investigated its Dnm1 (a dynamin-related protein)-dependent effects. Here, we demonstrate that Dnm1 functions as a mitochondrial fission component in U. maydis and mediates Lga2-induced mitochondrial fragmentation. Mitochondrial fusion occurred very...
Includes: Supplementary data
Journal Articles
J Cell Sci (2006) 119 (23): 4913–4925.
Published: 01 December 2006
...Yuka Eura; Naotada Ishihara; Toshihiko Oka; Katsuyoshi Mihara Mitofusin proteins 1 and 2 (Mfn1 and Mfn2, respectively) of the mammalian mitochondrial outer membrane are homologues of Drosophila FZO and yeast Fzo1, and both are essential for GTP-dependent mitochondrial fusion. We identified a 55-kDa...
Journal Articles
J Cell Sci (2004) 117 (13): 2653–2662.
Published: 01 June 2004
... 2004 Mitochondria Mitochondrial fusion Mitochondrial complementation Mitochondrial nucleoid Mitochondria are essential organelles that play a key role in fundamental cellular processes such as oxidative phosphorylation, calcium signaling and apoptosis ( Kroemer and Reed, 2000 ; Pozzan...