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Keywords: Mitochondrial fragmentation
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Journal Articles
ATPase family AAA domain-containing 3A is a novel anti-apoptotic factor in lung adenocarcinoma cells
Hsin-Yuan Fang, Chia-Ling Chang, Shu-Han Hsu, Chih-Yang Huang, Shu-Fen Chiang, Shiow-Her Chiou, Chun-Hua Huang, Yi-Ting Hsiao, Tze-Yi Lin, I-Ping Chiang, Wen-Hu Hsu, Sumio Sugano, Chih-Yi Chen, Ching-Yuang Lin, Wen-Je Ko, Kuan-Chih Chow
Journal:
Journal of Cell Science
J Cell Sci (2010) 123 (7): 1171–1180.
Published: 1 April 2010
... and confocal immunofluorescent microscopy. Our results show that ATAD3A is the major form expressed in LADC. Silencing of ATAD3A expression increased mitochondrial fragmentation and cisplatin sensitivity. Serum deprivation increased ATAD3A expression and drug resistance. These results suggest that ATAD3A could...
Includes: Supplementary data
