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Keywords: Mitochondrial disease
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Journal Articles

Large heterogeneity of mitochondrial DNA transcription and initiation of replication exposed by single-cell imaging

Laurent Chatre, Miria Ricchetti
Journal: Journal of Cell Science
J Cell Sci (2013) 126 (4): 914–926.
https://doi.org/10.1242/jcs.114322
Published: 15 February 2013
...-7213.2000 * Author for correspondence ( [email protected] ). 19 11 2012 © 2013. Published by The Company of Biologists Ltd 2013 DNA replication FISH Imaging Mitochondrial DNA Mitochondrial disease Transcription Mitochondria are ATP-producing organelles whose...
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Includes: Supplementary data
Journal Articles

MIDAS/GPP34, a nuclear gene product, regulates total mitochondrial mass in response to mitochondrial dysfunction

Naomi Nakashima-Kamimura, Sadamitsu Asoh, Yoshitomo Ishibashi, Yuri Mukai, Yujiro Shidara, Hideaki Oda, Kae Munakata, Yu-ichi Goto, Shigeo Ohta
Journal: Journal of Cell Science
J Cell Sci (2005) 118 (22): 5357–5367.
https://doi.org/10.1242/jcs.02645
Published: 15 November 2005
... (mitochondrial DNA absence sensitive factor) whose expression was enhanced by the absence of mitochondrial DNA (mtDNA). In patients with mitochondrial diseases, MIDAS expression was increased only in dysfunctional muscle fibers. A majority of MIDAS localized to mitochondria with a small fraction in the Golgi...
View articletitled, MIDAS/GPP34, a nuclear gene product, regulates total mitochondrial mass in response to mitochondrial dysfunction
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Includes: Supplementary data