...Elizabeth J. Lawrence; Marija Zanic; Luke M. Rice ABSTRACT CLIP-associating proteins (CLASPs) form an evolutionarily conserved family of regulatory factors that control microtubule dynamics and the organization of microtubule networks. The importance of CLASP activity has been appreciated for some...

.... , Krek , W. , Danuser , G. and Wittmann , T. ( 2010 ). Analysis of microtubule dynamic instability using a plus-end growth marker . Nat. Methods   7 , 761 - 768 . 10.1038/nmeth.1493 Micale , N. , Colleoni , S. , Postorino , G. , Pellicanò , A. , Zappalà , M...

... the negative effects of IO for live imaging. Fluorescence microscopy Phototoxicity Cell migration Mitochondrial dynamics Microtubule dynamics Adhesion dynamics Fluorescence microscopy provides a convenient, selective and sensitive way to observe living systems. Although modern microscopes...

... towards depolymerization in the lagging zone. Polymerization of microtubules behind the lagging zone has not been reported to date, suggesting that microtubule loss there is irreversible. In this Review, we discuss: (1) the regulation of microtubule dynamics in the phragmoplast zones during expansion; (2...

... no competing interests. 7 06 2013 24 09 2014 © 2014. Published by The Company of Biologists Ltd 2014 Microtubule Microtubule-associated protein MAP1S Microtubule dynamics Cytokinesis Regulating dynamic microtubule (MT) functions involves post-translational tubulin...

... by The Company of Biologists Ltd 2014 Actin cytoskeleton Actin treadmilling Adherens junctions Actomyosin Microtubule dynamics Cell polarization During normal development and in pathological contexts (such as cancer), opportunistic cell–cell contacts either are self-reinforcing, leading...

... regulation of microtubule dynamics in motile fibroblasts.   Cell   104 , 923 – 935 . 10.1016/S0092-8674(01)00288-4 Al-Bassam   J. , Kim   H. , Brouhard   G. , van Oijen   A. , Harrison   S. C. , Chang   F. ( 2010 ). CLASP promotes microtubule rescue by recruiting tubulin dimers...

... by The Company of Biologists Ltd 2013 DCC Signal transduction TUBB3 Axon guidance Microtubule dynamics Netrin In the nervous system, temporal and spatial information processing relies on a variety of functional neural circuitries. The formation of neural circuits during brain development...

... dynamics, and highlight the role of quantitative approaches in understanding the mitotic spindle design. * Author for correspondence ( mogilner@math.ucdavis.edu ) © 2010. 2010 Mitotic spindle Self-assembly Error correction Viscoelastic gel Microtubule dynamics Cytoskeleton mechanics...

...Tao Liu; Jennifer L. Rohn; Remigio Picone; Patricia Kunda; Buzz Baum Microtubule dynamics are dominated by events at microtubule plus ends as they switch between discrete phases of growth and shrinkage. Through their ability to generate force and direct polar cell transport, microtubules help...

...Timothy M. E. Scales; Shen Lin; Michaela Kraus; Robert G. Goold; Phillip R. Gordon-Weeks MAP1B is a developmentally regulated microtubule-associated phosphoprotein that regulates microtubule dynamics in growing axons and growth cones. We used mass spectrometry to map 28 phosphorylation sites...

...-anaphase transition and that Mast and dynein have antagonistic roles in the regulation of microtubule plus-end dynamics at kinetochores. Interestingly, a recent study revealed that in Schizosaccharomyces pombe many of the phenotypes associated with interphase microtubule dynamics arising from...

...Eiko Kawamura; Geoffrey O. Wasteneys MOR1, the Arabidopsis thaliana homologue of the Xenopus microtubule-associated protein MAP215, is required for spatial organization of the acentrosomal microtubule arrays of plant cells. To determine how loss of MOR1 function affects microtubule dynamics, we...

...Noriaki Ohkawa; Kazuko Fujitani; Eri Tokunaga; Shigeki Furuya; Kaoru Inokuchi The regulation of microtubule dynamics is important for the appropriate arborization of neuronal dendrites during development, which in turn is critical for the formation of functional neural networks. Here we show...

... to other areas of the cell surface. © The Company of Biologists Limited 2006 2006 Cadherins E-cadherin Microtubules Microtubule dynamics Classical cadherin adhesion molecules function as membrane-spanning macromolecular complexes. The binding properties of the cadherin ectodomains...

... Biol. 38 , 437 -446. Hush, J. M., Wadsworth, P., Callaham, D. A. and Hepler, P. K. ( 1994 ). Quantification of microtubule dynamics in living plant cells using fluorescence redistribution after photobleaching. J. Cell Sci. 107 , 775 -784. Kakimoto, T. and Shibaoka, H. ( 1992...

.... ‡ Authors for correspondence (e-mail: paul.nurse@mail.rockefeller.edu ; myamamot@ims.u-tokyo.ac.jp ) * These authors contributed equally to this work 30 7 2004 © The Company of Biologists Limited 2004 2004 Fission yeast Microtubule dynamics Mating Meiosis Dynactin...

... microtubule-binding domain during cell cycle progression. © The Company of Biologists Limited 2001 2001 Phosphorylation Microtubule binding Microtubule dynamics Stable microtubules Mitosis Microtubules (MTs) are dynamic polymers of tubulin that are involved in many diverse functions...

... to stabilize spindle microtubules, and that the observed defects in spindle assembly may result from enhanced microtubule dynamics in XMAP230-depleted extracts. * Author for correspondence (e-mail: gard@biology.utah.edu ) 22 09 1999 17 11 1999 © 1999 by Company of Biologists 1999...

... voltage electron microscopy . J. Cell Biol . 75 , 541 – 558 . 10.1083/jcb.75.2.541 Cassimeris , L. , Pryer , N. K. and Salmon , E. D. ( 1988 ). Real time observations of microtubule dynamic instability in living cells . J. Cell Biol . 107 , 2223 – 2231 . 10.1083/jcb...