1-20 of 160
Keywords: Microtubule
Close
Follow your search
Access your saved searches in your account

Would you like to receive an alert when new items match your search?
Close Modal
Sort by
Journal Articles
J Cell Sci jcs.258464.
Published: 10 June 2021
...T. Lynne Blasius; Yang Yue; Raghu Ram Prasad; Xinglei Liu; Arne Gennerich; Kristen J. Verhey The kinesin-4 member KIF7 plays critical roles in Hedgehog signaling in vertebrate cells. KIF7 is an atypical kinesin as it binds to microtubules but is immotile. We demonstrate that, like conventional...
Journal Articles
In collection:
Cytoskeleton , Polarity
J Cell Sci (2021) 134 (11): jcs258437.
Published: 07 June 2021
...Chengye Feng; Joseph M. Cleary; Gregory O. Kothe; Michelle C. Stone; Alexis T. Weiner; James I. Hertzler; William O. Hancock; Melissa M. Rolls ABSTRACT Axons and dendrites are distinguished by microtubule polarity. In Drosophila , dendrites are dominated by minus-end-out microtubules, whereas axons...
Includes: Supplementary data
Journal Articles
In collection:
Cytoskeleton
J Cell Sci (2021) 134 (10): jcs257543.
Published: 03 June 2021
...Neha Khetan; Gérard Pruliere; Celine Hebras; Janet Chenevert; Chaitanya A. Athale ABSTRACT Radial microtubule (MT) arrays or asters determine cell geometry in animal cells. Multiple asters interacting with motors, such as those in syncytia, form intracellular patterns, but the mechanical principles...
Includes: Supplementary data
Journal Articles
J Cell Sci (2021) 134 (10): jcs250001.
Published: 27 May 2021
...Patricia Wadsworth ABSTRACT During anaphase, a microtubule-containing structure called the midzone forms between the segregating chromosomes. The midzone is composed of an antiparallel array of microtubules and numerous microtubule-associated proteins that contribute to midzone formation and...
Includes: Supplementary data
Journal Articles
In collection:
Cytoskeleton
J Cell Sci (2021) 134 (4): jcs246496.
Published: 17 February 2021
... play an important role in cellular function and morphology. The biophysical properties of cells and tissues are determined by the cytoskeleton, consisting of dynamic networks of F-actin and microtubules, molecular motors, crosslinkers and other associated proteins, among other factors such as cell–cell...
Journal Articles
In collection:
Cilia and Flagella
J Cell Sci (2020) 133 (17): jcs249805.
Published: 11 September 2020
.... Using Chlamydomonas , we attenuated IFT-based tubulin transport of GFP–β-tubulin by altering the IFT74N–IFT81N tubulin-binding module and the C-terminal E-hook of tubulin. E-hook-deficient GFP–β-tubulin was incorporated into the axonemal microtubules, but its transport frequency by IFT was reduced by...
Includes: Supplementary data
Journal Articles
J Cell Sci (2020) 133 (16): jcs227355.
Published: 27 August 2020
...Christopher Nosala; Kari D. Hagen; Nicholas Hilton; Tiffany M. Chase; Kelci Jones; Rita Loudermilk; Kristofer Nguyen; Scott C. Dawson ABSTRACT Giardia lamblia , a widespread parasitic protozoan, attaches to the host gastrointestinal epithelium by using the ventral disc, a complex microtubule (MT...
Includes: Supplementary data
Journal Articles
J Cell Sci (2020) 133 (16): jcs246025.
Published: 25 August 2020
... kinetochores to facilitate chromosome alignment during mitosis. CENP-E Motor Kinetochore Mitosis Microtubule To maintain their genomic integrity, eukaryotic cells must distribute their DNA equally to the daughter cells. Spindle microtubules mediate the segregation of chromosomes by...
Includes: Supplementary data
Journal Articles
In collection:
Cilia and Flagella
J Cell Sci (2020) 133 (16): jcs245233.
Published: 21 August 2020
... Microtubule Radial spoke Cross-link mass spectrometry Motile cilia and flagella are ubiquitous organelles present in many eukaryotic cells and are important for diverse cellular functions. The core axonemal ultrastructure of motile cilia and flagella is composed of a characteristic ‘9 microtubule...
Includes: Supplementary data
Journal Articles
J Cell Sci (2020) 133 (13): jcs244798.
Published: 01 July 2020
... relies on the typical organization of osteoclast cytoskeleton components into a highly complex structure comprising actin, microtubules and other cytoskeletal proteins that constitutes the backbone of the bone resorption apparatus. The development of methods to differentiate osteoclasts in culture and...
Journal Articles
In collection:
Cytoskeleton
J Cell Sci (2020) 133 (11): jcs242842.
Published: 11 June 2020
... response to both GR agonist and antagonist ligand binding. The inhibitory effect on migration is prevented by GR knockdown with siRNA, confirming GR specificity, but not by actinomycin D treatment, suggesting a non-transcriptional mechanism. We identified a rapid onset increase in microtubule...
Includes: Supplementary data
Journal Articles
J Cell Sci (2020) 133 (11): jcs240234.
Published: 08 June 2020
... between microtubule motors and non-motor proteins. Defects in spindle assembly or changes in spindle dynamics are associated with diseases, such as cancer or developmental disorders. Here, we compared mitotic and meiotic spindles in fission yeast. We show that, even though mitotic and meiotic spindles...
Includes: Supplementary data
Journal Articles
In collection:
Cytoskeleton
J Cell Sci (2020) 133 (9): jcs241216.
Published: 14 May 2020
...Yinlong Song; Yikan Zhang; Ying Pan; Jianfeng He; Yan Wang; Wei Chen; Jing Guo; Haiteng Deng; Yi Xue; Xianyang Fang; Xin Liang ABSTRACT In cells, microtubule dynamics are regulated by plus-end tracking proteins (+TIPs). End-binding protein 1 (EB1, also known as MAPRE1) acts as a master regulator of...
Includes: Supplementary data
Journal Articles
In collection:
Cytoskeleton
J Cell Sci (2020) 133 (8): jcs232983.
Published: 24 April 2020
...Kristi McElmurry; Jessica E. Stone; Donghan Ma; Phillip Lamoureux; Yueyun Zhang; Michelle Steidemann; Lucas Fix; Fang Huang; Kyle E. Miller; Daniel M. Suter ABSTRACT Previously, we have shown that bulk microtubule (MT) movement correlates with neurite elongation, and blocking either dynein activity...
Includes: Supplementary data
Journal Articles
J Cell Sci (2020) 133 (3): jcs233791.
Published: 12 February 2020
... cortical formin mobility depended on microtubules and only moderately on actin, whereas class II formin (denoted For2) mobility solely depended on actin. Moreover, cortical For2A tightly correlated with the puncta labeled by the endocytic membrane dye FM4-64, and null mutants in class I formins did not...
Includes: Supplementary data
Journal Articles
J Cell Sci (2019) 132 (15): jcs233726.
Published: 07 August 2019
... hydrodynamic flow, motile cilia are organized and oriented into a polarized array. Basal bodies (BBs) nucleate and position motile cilia at the cell cortex. Cytoplasmic BB-associated microtubules are conserved structures that extend from BBs. By using the ciliate, Tetrahymena thermophila , combined with EM...
Includes: Supplementary data
Journal Articles
In collection:
Cytoskeleton
J Cell Sci (2019) 132 (11): jcs227850.
Published: 07 June 2019
...Anna Akhmanova; Michel O. Steinmetz ABSTRACT Microtubules are cytoskeletal filaments essential for numerous aspects of cell physiology. They are polarized polymeric tubes with a fast growing plus end and a slow growing minus end. In this Cell Science at a Glance article and the accompanying poster...
Includes: Supplementary data
Journal Articles
In collection:
Cytoskeleton
J Cell Sci (2019) 132 (10): jcs231118.
Published: 16 May 2019
...Thibault Courthéoux; David Reboutier; Thibaut Vazeille; Jean-Yves Cremet; Christelle Benaud; Isabelle Vernos; Claude Prigent ABSTRACT During mitosis, the cell sequentially constructs two microtubule-based spindles to ensure faithful segregation of chromosomes. A bipolar spindle first pulls apart...
Includes: Supplementary data
Journal Articles
J Cell Sci (2019) 132 (3): jcs222430.
Published: 11 February 2019
... is spatially restricted to the site of cell plate formation is unknown. Aggregation of cell-plate membrane starts near regions of microtubule overlap within the bipolar phragmoplast apparatus of the moss Physcomitrella patens . Since vesicle fusion generally requires coordination of vesicle tethering...
Includes: Supplementary data
Journal Articles
In collection:
Cytoskeleton
J Cell Sci (2018) 131 (20): jcs223107.
Published: 22 October 2018
...Martin Harterink; Stacey L. Edwards; Bart de Haan; Kah Wai Yau; Sander van den Heuvel; Lukas C. Kapitein; Kenneth G. Miller; Casper C. Hoogenraad ABSTRACT The specific organization of the neuronal microtubule cytoskeleton in axons and dendrites is an evolutionarily conserved determinant of neuronal...
Includes: Supplementary data