.... Cooperativity between selectin and integrin binding was evaluated by dose-response analysis, providing new insight into the signaling mechanism. Leukocyte adhesion Integrin activation Selectin Micropipette adhesion frequency assay Microfluidics National Institutes of Health http://dx.doi.org...

.... Published by The Company of Biologists Ltd 2019 Summary: Up-to-date cell biology tools that enable deconstruction of the complex environments through which cells move in tissues are demonstrated via a hand-drawn poster. Microfabrication Cell migration Microfluidics Micropatterning...

... and chemical cues remains incompletely understood. Here, we address this question by probing the efficiency of epidermal growth factor (EGF)-induced hMSC chemotaxis on substrates of varying stiffness (3, 30 and 600 kPa) inside a polydimethylsiloxane (PDMS) microfluidic device. Chemotactic speed was found...

... poorly understood. In principle, the flattening of invaginations and buds within the plasma membrane could provide this additional surface area, as recently shown for caveolae in animal cells. Here, we used microfluidics to study the rapid expansion of the yeast plasma membrane in protoplasts, which lack...