... the motor proteins and adaptors, or membrane trafficking. Here, we will discuss recent studies to highlight what is known about the regulation of endosomal vesicle positioning and transport by motors and cargo adaptors. We also emphasise that in vitro and cellular studies are often performed at different...

... in any medium provided that the original work is properly attributed. Summary: COPII vesicle formation and trafficking of plasma membrane proteins depend on the phosphorylated state of S134 in Erv14 Erv14 Cornichon Phosphorylation COPII vesicles Membrane trafficking Consejo...

... the translocation capacity of the cells. GLUT4 SNARE Syntaxin Membrane trafficking Diabetes UK http://dx.doi.org/10.13039/501100000361 15/0005246 17/0005605 17/0005724 18/0005847 18/0005905 19/0005978 Novo Nordisk Research Foundation http://dx.doi.org/10.13039/501100000329...

...-INBS-04 China Scholarship Council http://dx.doi.org/10.13039/501100004543 Salmonella Infection Effector protein Lysosome Molecular motor Membrane trafficking Summary: Salmonella replicates in host cells in a membrane compartment that it shapes with the help of host...

... . J. Biol. Chem. 272 , 672 - 679 . 10.1074/jbc.272.1.672 Mahajan , D. , Tie , H. C. , Chen , B. and Lu , L. ( 2019 ). Dopey1-Mon2 complex binds to dual-lipids and recruits kinesin-1 for membrane trafficking . Nat. Commun. 10 , 3218 . 10.1038/s41467-019-11056-5...

...Chun Wan; Lauren Crisman; Bing Wang; Yuan Tian; Shifeng Wang; Rui Yang; Ishara Datta; Toshifumi Nomura; Suzhao Li; Haijia Yu; Qian Yin; Jingshi Shen ABSTRACT Multimeric cargo adaptors such as AP2 play central roles in intracellular membrane trafficking. We recently discovered that the assembly...

.... intestinalis rewired host cell mitochondrial energy production and membrane trafficking in favor of parasitic development. Interestingly, the gene angiotensin converting enzyme 2 ( ACE2 ) is downregulated in Caco2 cells infected with E. intestinalis. The protein encoded by this gene has more recently...

...Miguel Hernandez-Gonzalez; Gabrielle Larocque; Michael Way ABSTRACT Membrane trafficking is an essential cellular process conserved across all eukaryotes, which regulates the uptake or release of macromolecules from cells, the composition of cellular membranes and organelle biogenesis...

... transporters preserved at the surface in eisosomes. Eisosomes Endosomal trafficking Glucose starvation Membrane trafficking Cell surface membrane protein cargoes perform diverse roles, including initiating signal transduction pathways, uptaking nutrients and maintaining the ionic balance...

... of the CV and the ciliary membrane biogenesis is achieved by vesicular membrane trafficking controlled by a cascade of small G proteins, including Rab11 and Rab8 (herein referring collectively to the Rab8a and Rab8b, and Rab11a and Rab11b forms) ( Knodler et al., 2010 ; Nachury et al., 2007 ; Westlake et...

... contact sites. SNARE Axonal growth Filopodia Lipid transfer protein Membrane contact site Membrane trafficking Association Française contre les Myopathies 10.13039/100013465 16612 Agence Nationale de la Recherche 10.13039/501100001665 ANR-13-BSV2-0018-02 ANR-16-CE16...

... products and water from the retina to the blood, recycling of retinal chromophores, absorption of scattered light and phagocytosis of the tips of the photoreceptor outer segments. These functions place a considerable membrane trafficking burden on the RPE. In this Cell Science at a Glance article...

.... Published by The Company of Biologists Ltd 2020 Summary: Microtubules are important regarding various steps of protein transport. Regulation of their functions is achieved by protein interactions but also by post-translational modifications of tubulin. Golgi complex Membrane trafficking...

... shown that FIP2 phosphorylation controls intracellular membrane trafficking related to cell polarity in epithelial cell lines ( Ducharme et al., 2006 ; Lapierre et al., 2012 ). Interestingly, phosphorylated FIP2 acts independently from myosin Vb and Rab11 ( Lapierre et al., 2012 ). Therefore, we...

... Ltd 2019 Summary: Why is membrane trafficking rate-limiting for release of constitutively secreted interleukin-6? We propose that cells monitor and adjust cytokine secretion rates for prevention of septic shock. Cytokine secretion Exocytosis Interleukin 6 Membrane trafficking...

... polarized membrane trafficking driven by Rho GTPase-mediated cytoskeletal remodeling. We identify the Rho GTPase-activating protein deleted in liver cancer 3 (DLC3; also known as STARD8) as an integral component of the endosomal transport and sorting machinery. We provide evidence for the direct regulation...

... polarized Golgi trafficking to promote invasive breast cancer programs . EMBO Rep.   17 , 1061 - 1080 . 10.15252/embr.201642032 Kajiho , H. , Kajiho , Y. and Scita , G. ( 2018 ). Harnessing membrane trafficking to promote cancer spreading and invasion: the case of RAB2A . Small...

... localized at tubular endosomes. The Rab10–KIF13 complex is likely to regulate the formation of tubular endosomes. Rab10 Membrane trafficking Organelle biogenesis Small GTPase Rab Tubular endosome Higher eukaryotic cells contain several functionally distinct endosomal compartments...

... complex functions as a central organizing organelle ( Emr et al., 2009 ; Farquhar and Palade, 1998 ). This central Golgi stack processes and facilitates the targeting of newly synthesized cargoes as they emerge from the ERGIC and traffic through to the TGN. Golgi Arf GTPase GBF1 Membrane...

... of an unstacked Golgi organelle in a non-parasitic eukaryote, other than fungi. We provide a comprehensive list of Golgi-associated membrane trafficking genes encoded in two species of Naegleria and show that nearly all are expressed in mouse-passaged N. fowleri cells. We then study distribution of the Golgi...