...Pawel Leznicki; Hayden O. Schneider; Jada V. Harvey; Wei Q. Shi; Stephen High ABSTRACT Membrane proteins destined for lipid droplets (LDs), a major intracellular storage site for neutral lipids, are inserted into the endoplasmic reticulum (ER) and then trafficked to LDs where they reside...

... capture) or by bulk flow. For membrane proteins, a third mechanism, based on the interaction of their transmembrane domain (TMD) with lipid microdomains, must also be considered. In this Commentary, I review evidence in favor of the idea that partitioning of TMDs into bilayer domains that are endowed...

... Coarse-graining Simulations Multiscaling Lipid bilayers Membrane proteins Cell membranes comprise a heterogeneous mixture of membrane proteins and lipids, and are far more complex than frequently realized. Typical eukaryotic plasma membranes, for instance, contain hundreds of different lipids...

.... Lipid transfer Longin Membrane proteins SNARE Vesicular trafficking Eukaryotic cells possess an endomembrane system that comprises membrane-bound organelles – including the nucleus, endoplasmic reticulum (ER), Golgi complex, endosomes, lysosomes, vesicles and plasma membrane – that carry out...

... © The Company of Biologists Limited 2007 2007 Endoplasmic reticulum Membrane proteins Hsc70 Hsp40 Hsp90 The majority of proteins in higher eukaryotes are synthesised in the cytosol before being targeted to their final subcellular destination, and the presence of several distinct...

... The Company of Biologists Limited 2006 2006 Uroplakins Tetraspanins Endoplasmic reticulum Membrane proteins The mammalian urinary bladder is lined by urothelium, a stratified epithelium that protects the underlying tissues from the potentially harmful effects of the urine content...

... functional role for the mammalian Crumbs FERM binding domain. * Author for correspondence (e-mail: [email protected] ) 31 3 2005 © The Company of Biologists Limited 2005 2005 FERM Membrane Proteins Claudin Mammary Epithelia Zona occludens The defining characteristic...

... ) 19 9 2003 © The Company of Biologists Limited 2004 2004 NIS (sodium/iodide symporter) ITD (iodide transport defect) Thyroid Membrane proteins Iodide (I - ) is an essential constituent of the thyroid hormones T 3 and T 4 (triiodothyronine and thyroxine, or tetraiodothyronine...

... the influence of the peroxisomal membrane on the formation of a subset of the investigated protein-protein interactions. * Author for correspondence (e-mail: [email protected] ) 21 5 2003 © The Company of Biologists Limited 2003 2003 Membrane proteins Protein interaction...

...., Moreira, J. E., Smith, C. L.,Presley, J. F., Worman, H. J. and Lippincott-Schwartz, J. ( 1997 ). Nuclear membrane dynamics and reassembly in living cells:targeting of an inner nuclear membrane protein in interphase and mitosis. J. Cell Biol. 138 , 1193 -1206. Ellis, J. A., Craxton, M., Yates, J. R...

... clone, WIF12-E, which is extinguished for most liver-specific functions, and with the common hepatoma parent, Fao. By immunoblot analysis, the levels of expression of eight plasma membrane proteins were higher in the WIF-B cells than in either of the other two cell lines and ranged from 10 to 200...

...Erica Tenbroek; Mark Arneson; Lisa Jarvis; Charles Louis ABSTRACT MP20 is an intrinsic membrane protein previously identified in mammalian lens fiber cells. To identify a possible role for this protein in the lens, the distribution of MP20 and connexin46 has now been examined. Western...

...David Gingell; Norman Owens © 1992 by Company of Biologists 1992 adhesion membrane proteins cytoskeleton A great deal is known about the ways in which diffusible molecules bind to receptors and trigger transductive mechanisms located in the plasma membrane. Only recently has...

... for lysosomal glycoprotein (Igp) membrane markers but were morphologically distinct In most experiments, rat-mouse cell syncytia were formed by u.v.-inactivated Sindbis virus-mediated fusion. By immunogold electron microscopy of syncytia, extensive intermixing of species-specific lysosomal membrane proteins...

... represented on SDS-polyacrylamide gels from peroxisomes induced by oleic acid or D-alanine were found to be very different from those of peroxisomes induced by methanol. In order to differentiate between membrane proteins that have specific functions in pathways of substrate utilization from those with more...

...G. Neil Green; William Hansen; Peter Walter ABSTRACT We have used protein-fusions to study in Saccharomyces cerevisiae the topology and integration of arginine permease. Since this membrane protein does not contain a cleavable signal sequence, we sought to identify the first internal signal...