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Keywords: Membrane integration
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Journal Articles
J Cell Sci (2009) 122 (20): 3605–3612.
Published: 15 October 2009
... reticulum Membrane integration Post-translational The defining feature of a tail-anchored protein is the presence of a single transmembrane (TM) segment at the extreme C-terminus of the polypeptide ( Kutay et al., 1993 ). This TM segment provides a targeting signal for the delivery of the protein...
Journal Articles
J Cell Sci (2009) 122 (11): 1768–1777.
Published: 01 June 2009
...Benedict C. S. Cross; Stephen High The membrane integration of polytopic proteins is coordinated at the endoplasmic reticulum (ER) by the conserved Sec61 translocon, which facilitates the lateral release of transmembrane (TM) segments into the lipid phase during polypeptide translocation. Here we...
Includes: Supplementary data