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Keywords: Membrane blebbing
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Journal Articles
J Cell Sci (2011) 124 (8): 1256–1267.
Published: 15 April 2011
... in membrane blebbing. Unlike elongated A375 melanoma cells, rounded A375 cells do not display any obvious morphological front–back polarisation, although polarisation is thought to be a prerequisite for cell movement. We show that blebbing A375 cells are polarised, with ezrin (a linker between the plasma...
Includes: Multimedia, Supplementary data
Journal Articles
J Cell Sci (2010) 123 (8): 1235–1246.
Published: 15 April 2010
... repeated episodes of cell contraction (often associated with membrane blebbing) followed by extension of lamellae and membrane ruffling ( Fig. 1B ; supplementary material Movie 1 ). The periodicity of the expansion-contraction cycles was approximately 20 minutes and several cells underwent 12-15 cycles...
Includes: Multimedia, Supplementary data
Journal Articles
J Cell Sci (2007) 120 (21): 3820–3829.
Published: 1 November 2007
... distinct kinetics. These reorganizations of the PM are controlled by Rho but not Rac or Cdc42 GTPase signalling pathways. SH4-induced membrane blebbing requires the membrane association of the SH4 domain, is regulated by the activities of Rock kinase and myosin II ATPase, and depends on the integrity of F...
Includes: Multimedia, Supplementary data