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Keywords: Mechanical stress
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Journal Articles
In collection:
Mechanobiology
J Cell Sci (2021) 134 (13): jcs256313.
Published: 12 July 2021
... membrane voltage in mammary epithelial cells. Mechanical stress Tissue morphodynamics Bioelectricity National Institutes of Health http://dx.doi.org/10.13039/100000002 CA187692 Howard Hughes Medical Institute http://dx.doi.org/10.13039/100000011 National Science...
Includes: Supplementary data
Journal Articles
J Cell Sci (2016) 129 (2): 290–297.
Published: 15 January 2016
... on endothelial cells, and this expression provides a Na + entry pathway and confers a mechanism by which cells can respond to mechanical stress. However, ENaC expression is suppressed until the physiological environment changes; in this case, the appearance of inflammation. Pro-inflammatory factors greatly...
Journal Articles
J Cell Sci (2015) 128 (15): 2766–2780.
Published: 1 August 2015
... by The Company of Biologists Ltd 2015 Highlighted Article: Decreased membrane binding of PACSIN2 upon its PKC-mediated phosphorylation at serine 313 is shown to trigger the removal of caveolae from the plasma membrane. Caveolae BAR domain Phosphorylation Protein kinase C Mechanical stress...
Includes: Supplementary data
Journal Articles
J Cell Sci (2013) 126 (16): 3697–3712.
Published: 15 August 2013
... activation, but also for activation of the canonical TGFβ signaling intermediate Smad3. We show that Smad3 activation is an essential requirement for CTGF upregulation in MC under mechanical stress. Pak1 regulates Smad3 C-terminal phosphorylation and transcriptional activation. However, a second signaling...
Includes: Supplementary data
Journal Articles
J Cell Sci (2012) 125 (3): 743–750.
Published: 1 February 2012
...Fanjie Meng; Frederick Sachs Mechanical stress is an unmapped source of free energy in cells. Mapping the stress fields in a heterogeneous time-dependent environment like that found in cells requires probes that are specific for different proteins and respond to biologically relevant forces...
Includes: Multimedia, Supplementary data
Journal Articles
J Cell Sci (2008) 121 (4): 496–503.
Published: 15 February 2008
[email protected] ) 19 11 2007 © The Company of Biologists Limited 2008 2008 Actin Mechanosensitive channel Mechanical stress Stress fiber Mechanosensitive (MS) channels are expressed in a variety of cells ( Sachs, 1991 ). They are thought to play crucial roles not only...
Includes: Supplementary data
Journal Articles
J Cell Sci (2005) 118 (5): 937–949.
Published: 1 March 2005
... characterizing smooth-muscle cells in vivo is a continuous exposure to mechanical stretching in the organs. To study the involvement of Hic-5 in cellular responses to mechanical stress, we exposed mouse embryo fibroblasts to a uni-axial cyclic stretching and found that Hic-5 was relocalized from focal adhesions...
Journal Articles
J Cell Sci (2001) 114 (6): 1221–1227.
Published: 15 March 2001
...Yasuhiro Sawada; Kozo Nakamura; Koichi Doi; Kohsuke Takeda; Kei Tobiume; Masao Saitoh; Keiichi Morita; Issei Komuro; Kurt De Vos; Michael Sheetz; Hidenori Ichijo ABSTRACT Mechanical force or mechanical stress modulates intracellular signal pathways, including the mitogen-activated protein kinase...
Journal Articles
J Cell Sci (2000) 113 (20): 3583–3591.
Published: 15 October 2000
... stress in vivo. Chicken anterior latissimus dorsi muscle (ALD) was mechanically stressed by applying a load to the left wing. Within 36 hours of loading, expression of tenascin-C protein was ectopically induced in the endomysium along the surface of single muscle fibers throughout the ALD, whereas...
Journal Articles