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Keywords: Mammary gland
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Journal Articles
In collection:
Cell migration
J Cell Sci (2023) 136 (1): jcs259275.
Published: 5 January 2023
... imaging to study the real-time cellular contributions to these processes ( Nguyen-Ngoc et al., 2015 ). Our leading hypothesis for molecular regulation of bifurcation was TGF-β signaling, as it has been identified as a key regulator of side-branching and TEB migration in the mammary gland ( Kahata et al...
Includes: Supplementary data
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Polarity
J Cell Sci (2021) 134 (22): jcs258905.
Published: 23 November 2021
... acts coordinately with basement membrane components to trigger mammary cyst formation. Mammary gland Syntaxin4 Epithelial morphogenesis Epimorphin Basement membrane Epithelial–mesenchymal transition Japan Society for the Promotion of Science http://dx.doi.org/10.13039/501100001691...
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Mechanobiology
J Cell Sci (2021) 134 (1): jcs248849.
Published: 8 January 2021
...-specific Piezo1 deletion. These findings support a multifaceted system of chemical and mechanical sensing in the mammary gland, and a protective redundancy that ensures continued lactational competence and offspring survival. * Author for correspondence ( [email protected] ) Handling Editor...
Includes: Supplementary data
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J Cell Sci (2010) 123 (19): 3316–3328.
Published: 1 October 2010
... Mammary gland Epithelial Cell polarity PKCζ Proliferation Breast cancer Mammary epithelial cells (MECs) form acini when cultured on laminin-rich extracellular matrix (ECM) in vitro. Acini are reminiscent of epithelial cysts seen in the mammary gland in vivo; the constituent cells...
Includes: Supplementary data
Journal Articles
J Cell Sci (2010) 123 (4): 606–618.
Published: 15 February 2010
...Stephanie B. Greene; Preethi H. Gunaratne; Scott M. Hammond; Jeffrey M. Rosen In an effort to understand the potential role of microRNAs (miRNAs) in mammary-gland stem or progenitor cells, miRNA microarrays were performed on subpopulations of the mouse mammary epithelial cell (MEC) line COMMA-DβGeo...
Includes: Supplementary data
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J Cell Sci (2003) 116 (4): 675–682.
Published: 15 February 2003
...-binding proteins (IGFBPs),there is currently no experimental evidence that IGFBPs regulate the survival function of IGFs in the mammary gland. We have examined IGFBP expression during mammary gland development and studied the effects of IGFBPs on IGF-mediated survival and signalling in mammary epithelial...
Journal Articles
J Cell Sci (2002) 115 (23): 4419–4431.
Published: 1 December 2002
... inhibitor BB94,indicating that this morphogenetic process is likely to require MMP activity. Collectively, our results provide evidence that RA promotes lumen formation by mammary epithelial cells in vitro and suggest that it plays a similar role during mammary gland development in vivo. When grown...
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J Cell Sci (2000) 113 (12): 2129–2138.
Published: 15 June 2000
...Stuart Naylor; Matthew J. Smalley; David Robertson; Barry A. Gusterson; Paul A. W. Edwards; Trevor C. Dale ABSTRACT Several Wnt genes are expressed in the postnatal mouse mammary gland and are thought to be involved in mammary gland development. Ectopic expression of Wnt-1, which is not normally...
Journal Articles
J Cell Sci (2000) 113 (5): 849–858.
Published: 1 March 2000
... expression Epithelial-mesenchymal interaction Mammary gland Tissue-specific gene expression in epithelial cells is achieved through integration of multiple and sustained signals from the cellular microenvironment. Mouse mammary epithelial cells isolated from mid-pregnant mammary glands form acinus...
Journal Articles
J Cell Sci (2000) 113 (5): 795–806.
Published: 1 March 2000
...P. Schedin; R. Strange; T. Mitrenga; P. Wolfe; M. Kaeck ABSTRACT Mammary gland form and function are regulated by interactions between epithelium and extracellular matrix. Major glycoprotein components of extracellular matrix have been identified that give survival, proliferation...
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