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Keywords: MLL
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Journal Articles

MLL regulates the actin cytoskeleton and cell migration by stabilising Rho GTPases via the expression of RhoGDI1

In collection:
Cell migration , Cytoskeleton
Akash Chinchole, Kaisar Ahmad Lone, Shweta Tyagi
Journal: Journal of Cell Science
J Cell Sci (2022) 135 (20): jcs260042.
https://doi.org/10.1242/jcs.260042
Published: 20 October 2022
...Akash Chinchole; Kaisar Ahmad Lone; Shweta Tyagi ABSTRACT Attainment of proper cell shape and the regulation of cell migration are essential processes in the development of an organism. The mixed lineage leukemia (MLL or KMT2A) protein, a histone 3 lysine 4 (H3K4) methyltransferase, plays...
View article titled, <span class="search-highlight">MLL</span> regulates the actin cytoskeleton and cell migration by stabilising Rho GTPases via the expression of RhoGDI1
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Includes: Supplementary data
Journal Articles

MLL1, a H3K4 methyltransferase, regulates the TNFα-stimulated activation of genes downstream of NF-κB

Xiang Wang, Kun Zhu, Shangze Li, Yifang Liao, Runlei Du, Xiaodong Zhang, Hong-Bing Shu, An-Yuan Guo, Lianyun Li, Min Wu
Journal: Journal of Cell Science
J Cell Sci (2012) 125 (17): 4058–4066.
https://doi.org/10.1242/jcs.103531
Published: 1 September 2012
...Xiang Wang; Kun Zhu; Shangze Li; Yifang Liao; Runlei Du; Xiaodong Zhang; Hong-Bing Shu; An-Yuan Guo; Lianyun Li; Min Wu Summary Genes of the mixed lineage leukemia (MLL) family regulate transcription by methylating histone H3K4. Six members of the MLL family exist in humans, including SETD1A...
View article titled, MLL1, a H3K4 methyltransferase, regulates the TNFα-stimulated activation of genes downstream of NF-κB
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Includes: Supplementary data
Journal Articles

Proteolytically cleaved MLL subunits are susceptible to distinct degradation pathways

Akihiko Yokoyama, Francesca Ficara, Mark J. Murphy, Christian Meisel, Alpana Naresh, Issay Kitabayashi, Michael L. Cleary
Journal: Journal of Cell Science
J Cell Sci (2011) 124 (13): 2208–2219.
https://doi.org/10.1242/jcs.080523
Published: 1 July 2011
...Akihiko Yokoyama; Francesca Ficara; Mark J. Murphy; Christian Meisel; Alpana Naresh; Issay Kitabayashi; Michael L. Cleary The mixed lineage leukemia (MLL) proto-oncogenic protein is a histone-lysine N -methyltransferase that is produced by proteolytic cleavage and self-association of the respective...
View article titled, Proteolytically cleaved <span class="search-highlight">MLL</span> subunits are susceptible to distinct degradation pathways
Open the PDF for Proteolytically cleaved <span class="search-highlight">MLL</span> subunits are susceptible to distinct degradation pathways in another window
Includes: Supplementary data