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Keywords: MEF2
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Journal Articles
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Autophagy
J Cell Sci (2016) 129 (21): 4076–4090.
Published: 1 November 2016
...Stephanie Wales Tobin; Dabo Yang; John Girgis; Ali Farahzad; Alexandre Blais; John C. McDermott ABSTRACT Mycocyte enhancer factor 2 (MEF2) and activator protein 1 (AP-1) transcription complexes have been individually implicated in myogenesis, but their genetic interaction has not previously been...
Includes: Supplementary data
Journal Articles
J Cell Sci (2015) 128 (4): 631–637.
Published: 15 February 2015
...Valeria Runfola; Soji Sebastian; F. Jeffrey Dilworth; Davide Gabellini ABSTRACT Among the Mef2 family of transcription factors, Mef2D is unique in that it undergoes tissue-specific splicing to generate an isoform that is essential for muscle differentiation. However, the mechanisms mediating...
Includes: Supplementary data
Journal Articles
J Cell Sci (2012) 125 (22): 5329–5337.
Published: 15 November 2012
... dysregulation of Foxo and Mef2 downstream targets. Utilizing an array of technologies, we establish that Foxk1 represses the transcriptional activity of Foxo4 and Mef2 and physically interacts with Foxo4 and Mef2, thus promoting MPC proliferation and antagonizing the myogenic lineage differentiation program...
Includes: Supplementary data
Journal Articles
J Cell Sci (2005) 118 (10): 2295–2302.
Published: 15 May 2005
... factor activity in skeletal muscle fibers. Myocyte enhancer factor 2 (MEF2)-dependent transcriptional activity was increased by innervation, but unaffected by IP3R1 activity. The results indicate that IP3R1 activity regulates muscle fiber type-specific gene expression in innervated muscle fibers...
Journal Articles
J Cell Sci (2004) 117 (14): 3021–3029.
Published: 15 June 2004
... for their mutual interaction. PHB2 acts as a transcriptional repressor in cells. PHB2 interacts with both MyoD and MEF2, and represses both MyoD- and MEF2-dependent gene transcription. Furthermore, binding of PHB2 to both MyoD and MEF2 significantly decreases upon myogenic differentiation. When stably expressed...