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Keywords: MBF
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Journal Articles

An essential role for dNTP homeostasis following CDK-induced replication stress

Open Access
Chen-Chun Pai, Kuo-Feng Hsu, Samuel C. Durley, Andrea Keszthelyi, Stephen E. Kearsey, Charalampos Rallis, Lisa K. Folkes, Rachel Deegan, Sarah E. Wilkins, Sophia X. Pfister, Nagore De León, Christopher J. Schofield, Jürg Bähler, Antony M. Carr, Timothy C. Humphrey
Journal: Journal of Cell Science
J Cell Sci (2019) 132 (6): jcs226969.
https://doi.org/10.1242/jcs.226969
Published: 25 March 2019
... Set2-dependent MBF-induced expression of Cdc22, the catalytic subunit of ribonucleotide reductase (RNR). Disrupting dNTP synthesis following Wee1 inactivation, through abrogating Set2-dependent H3K36 tri-methylation or DNA integrity checkpoint inactivation results in critically low dNTP levels...
View article titled, An essential role for dNTP homeostasis following CDK-induced replication stress
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Includes: Supplementary data
Journal Articles

Nutritional cell cycle reprogramming reveals that inhibition of Cdk1 is required for proper MBF-dependent transcription

Free
Angela Rubio, Natalia García-Blanco, Alicia Vázquez-Bolado, María Belén Suárez, Sergio Moreno
Journal: Journal of Cell Science
J Cell Sci (2018) 131 (18): jcs218743.
https://doi.org/10.1242/jcs.218743
Published: 20 September 2018
... and the anaphase-promoting complex/cyclosome (APC/C) activator Ste9 in nitrogen-rich and nitrogen-poor media. Rum1 and Ste9 are dispensable for cell division in nitrogen-rich medium. However, in nitrogen-poor medium they are essential for generating a proper wave of MluI cell-cycle box binding factor (MBF...
View article titled, Nutritional cell cycle reprogramming reveals that inhibition of Cdk1 is required for proper MBF-dependent transcription
Open the PDF for Nutritional cell cycle reprogramming reveals that inhibition of Cdk1 is required for proper MBF-dependent transcription in another window
Includes: Supplementary data