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Keywords: MAPK/Erk
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Journal Articles

Mitogen-activated protein kinase (MAPK/ERK) regulates adenomatous polyposis coli during growth-factor-induced cell extension

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Hector Y. Caro-Gonzalez, Lene N. Nejsum, Kathleen A. Siemers, Thomas A. Shaler, W. James Nelson, Angela I. M. Barth
Journal: Journal of Cell Science
J Cell Sci (2012) 125 (5): 1247–1258.
https://doi.org/10.1242/jcs.095166
Published: 1 March 2012
... directly. We show here that NGF- and EGF-induced initial cell extensions result in APC phosphorylation by the MAPK/ERK pathway, which, in parallel with inhibition of GSK-3β, promotes localization of APC to the tip of cell extensions. Whereas GSK-3β inhibition promotes APC binding and stabilization...
View articletitled, Mitogen-activated protein kinase (MAPK/ERK) regulates adenomatous polyposis coli during growth-factor-induced cell extension
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Includes: Supplementary data
Journal Articles

MAPK/Erk-dependent phosphorylation of synapsin mediates formation of functional synapses and short-term homosynaptic plasticity

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Carlo Natale Giuseppe Giachello, Ferdinando Fiumara, Caterina Giacomini, Anna Corradi, Chiara Milanese, Mirella Ghirardi, Fabio Benfenati, Pier Giorgio Montarolo
Journal: Journal of Cell Science
J Cell Sci (2010) 123 (6): 881–893.
https://doi.org/10.1242/jcs.056846
Published: 15 March 2010
...Carlo Natale Giuseppe Giachello; Ferdinando Fiumara; Caterina Giacomini; Anna Corradi; Chiara Milanese; Mirella Ghirardi; Fabio Benfenati; Pier Giorgio Montarolo MAPK/Erk is a protein kinase activated by neurotrophic factors involved in synapse formation and plasticity, which acts at both...
View articletitled, MAPK/Erk-dependent phosphorylation of synapsin mediates formation of functional synapses and short-term homosynaptic plasticity
Open the PDF for MAPK/Erk-dependent phosphorylation of synapsin mediates formation of functional synapses and short-term homosynaptic plasticity in another window
Includes: Supplementary data