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Keywords: Lysosome positioning
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Journal Articles
In collection:
Cytoskeleton
Kaiyuan Wu, Lingdi Wang, Yong Chen, Mehdi Pirooznia, Komudi Singh, Sarah Wälde, Ralph H. Kehlenbach, Iain Scott, Marjan Gucek, Michael N. Sack
Journal:
Journal of Cell Science
J Cell Sci (2018) 131 (22): jcs221036.
Published: 20 November 2018
... GCN5L1 to α-tubulin. Finally, we find that genetic depletion of GCN5L1 promotes perinuclear lysosome accumulation and histone deacetylase inhibition partially restores lysosomal positioning. We conclude that the interactions of GCN5L1, RanBP2 and αTAT1 function in concert to control α-tubulin acetylation...
Includes: Supplementary data
Journal Articles
Journal:
Journal of Cell Science
J Cell Sci (2017) 130 (9): 1637–1651.
Published: 1 May 2017
... provided that the original work is properly attributed. Summary: The lysosomal kinesin-1 cargo adaptor SKIP is shown to interact with kinesin-1 via both its heavy and light chains. A new stepwise hierarchical model for kinesin-1 activation is proposed. Kinesin-1 SKIP Lysosome positioning...
Includes: Supplementary data