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Keywords: Lymphopoiesis
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Journal Articles
Apolipoprotein A1 deficiency in mice primes bone marrow stem cells for T cell lymphopoiesis
Open AccessAmber B. Ouweneel, Myrthe E. Reiche, Olga S. C. Snip, Robbert Wever, Ezra J. van der Wel, Frank H. Schaftenaar, Soňa Kauerova, Esther Lutgens, Miranda Van Eck, Menno Hoekstra
Journal:
Journal of Cell Science
J Cell Sci (2022) 135 (5): jcs258901.
Published: 16 November 2021
... sizes and collagen contents were similar in the two groups of bone marrow recipients. In conclusion, systemic lack of APOA1 primes bone marrow stem cells for T cell lymphopoiesis. Our data provide novel evidence for a regulatory role of HDL in bone marrow functioning in normolipidemic mice...
Includes: Supplementary data