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Keywords: Living mammalian cellsClose
Alexandre E. Escargueil, Virginie Poindessous, Daniele Grazziotin Soares, Alain Sarasin, Peter R. Cook, Annette K. Larsen
Journal: Journal of Cell Science
J Cell Sci (2008) 121 (8): 1275–1283.
Published: 15 April 2008
... tool to characterize TCR-associated processes in vivo. Here, we characterize the influence of irofulven on Pol II activity, stability and mobility in living mammalian cells. Our results demonstrate that irofulven induces specific inhibition of nucleoplasmic RNA synthesis, an important decrease of Pol...
Includes: Supplementary data