... , and displays a complicated lipid-binding selectivity for both phospholipid head groups and fatty acid chain saturation. SPIKE1-DHR3 is predicted to adopt a C2-domain structure and functions as part of a tandem C2 array that enables reversible clustering at the cell apex. This work provides mechanistic insight...

... Autophagosome Phagophore ATG16L1 Atg16 Lipid binding Membrane recruitment Single-membrane lipidation Cancer Research UK 10.13039/501100000289 C52370/A21586 Autophagosomes are distinct double-membrane vesicles that form de novo to encapsulate and deliver cellular components...

... of Biologists Limited 2009 2009 Cortical ER Plasma membrane Sorting signal Lipid binding Sec-independent trafficking The endoplasmic reticulum (ER) is an organelle that forms contacts with many other membranes, and these contacts are specialised for traffic of both material and information...