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Keywords: Leukocyte
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Journal Articles
In collection:
Adhesion , Mitochondria
J Cell Sci (2020) 133 (17): jcs248880.
Published: 04 September 2020
... neutrophil migration seen upon MFN2 depletion. Our result in leukocytes is consistent with previous results in murine fibroblasts ( de Brito and Scorrano, 2008 ) showing that knocking out Mfn2 results in excessive cytosolic Ca 2+ and defective mitochondrial Ca 2+ uptake. Intriguingly, chronic blockade...
Includes: Supplementary data
Journal Articles
J Cell Sci (2015) 128 (9): 1718–1731.
Published: 01 May 2015
...@bcw.edu ) Competing interests The authors declare no competing or financial interests. 29 7 2014 2 3 2015 © 2015. Published by The Company of Biologists Ltd 2015 Integrin cytoplasmic domain Inside‐out activation Talin Kindlin Platelet Leukocyte Integrins are...
Includes: Supplementary data
Journal Articles
J Cell Sci (2014) 127 (20): 4381–4395.
Published: 15 October 2014
... . Using genetically encoded bioprobes and high-resolution live imaging, we reveal the existence of F-actin oscillations in the trailing edge and constant repositioning of the microtubule organizing center (MTOC) to direct leukocyte migration in wounded medaka fish larvae ( Oryzias latipes ). Genetic...
Includes: Supplementary data
Journal Articles
In collection:
Imaging
J Cell Sci (2014) 127 (17): 3720–3734.
Published: 01 September 2014
... Radmacher, 2000 ; Wakatsuki et al., 2001 ). Detailed study of our dynamic imaging experiments revealed several important findings. First, although the role of lateral migration has often been posited to be simply a means of getting leukocytes to the junctions to allow for paracellular diapedesis, we...
Includes: Supplementary data
Journal Articles
J Cell Sci (2014) 127 (3): 620–629.
Published: 01 February 2014
... of neutrophils with EC junctions prior to transendothelial cell migration (TEM), collectively resulting in significantly reduced extravasation. Pharmacological blockade of the leukocyte integrin MAC-1 indicated that some ICAM-2-dependent functions might be mediated through ligation of this integrin...
Includes: Supplementary data
Journal Articles
J Cell Sci (2013) 126 (6): 1416–1428.
Published: 15 March 2013
...-regulation of two enzymatic activities that reside in the same molecule with profound biological consequences in leukocyte cell migration. * Author for correspondence ( julian.cambronero@wright.edu ) 19 12 2012 © 2013. Published by The Company of Biologists Ltd 2013 HL-60 cells Cell...
Journal Articles
J Cell Sci (2009) 122 (17): 3025–3035.
Published: 01 September 2009
...Christopher V. Carman Immune-system functions require that blood leukocytes continuously traffic throughout the body and repeatedly cross endothelial barriers (i.e. diapedese) as they enter (intravasate) and exit (extravasate) the circulation. The very earliest studies to characterize diapedesis...
Journal Articles
J Cell Sci (2009) 122 (2): 268–277.
Published: 15 January 2009
... markedly impaired. * Author for correspondence (e-mail: elisabetta.dejana@ifom-ieo-campus.it ) 24 10 2008 © The Company of Biologists Limited 2009 2009 Integrins JAM Leukocyte Chemotaxis JAM-A (also known as F11R or JAM1) was the first member of the junctional adhesion...
Includes: Supplementary data
Journal Articles
J Cell Sci (2006) 119 (11): 2375–2385.
Published: 01 June 2006
...: yolanda.calle@kcl.ac.uk ; gareth.jones@kcl.ac.uk ) 15 2 2006 © The Company of Biologists Limited 2006 2006 Cell motility Leukocyte Dendritic cell Podosome Cell adhesion Calpain Cell locomotion involves a highly regulated cycle of assembly and disassembly of cell adhesions with...
Includes: Multimedia, Supplementary data
Journal Articles
J Cell Sci (2004) 117 (12): 2503–2511.
Published: 15 May 2004
...William D. Hanley; Denis Wirtz; Konstantinos Konstantopoulos Leukocytes are recruited from the bloodstream to sites of inflammation by the selectin family of adhesion receptors. In vivo and in vitro studies reveal distinctive rolling velocities of polymorphonuclear leukocytes over E-, P- and L...
Includes: Supplementary data
Journal Articles
J Cell Sci (2003) 116 (12): 2531–2539.
Published: 15 June 2003
...Ewa P. Wojcikiewicz; Xiaohui Zhang; Aileen Chen; Vincent T. Moy The interaction of leukocyte function-associated antigen-1 (LFA-1) and intercellular adhesion molecule-1 (ICAM-1) is central to the regulation of adhesion in leukocytes. In this report, we investigated the mechanisms by which phorbol...