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Keywords: Leptomycin BClose
Richard A. Lewis, Juanjuan Li, Nicholas E. E. Allenby, Jeffery Errington, Jacqueline Hayles, Paul Nurse
J Cell Sci (2017) 130 (18): 3173–3185.
Published: 15 September 2017
... cell morphology-related phenotype of rounded cells. As a proof of principle, we purified four of these activities, one of which is a novel compound and three that are previously known compounds, leptomycin B, streptonigrin and cycloheximide. In this study, we have also shown novel effects for two of...
Includes: Supplementary data
J Cell Sci (2001) 114 (24): 4407–4419.
Published: 15 December 2001
... that contain both p80-coilin and the survival of motor neurons protein (SMN) and not in bodies that contain p80-coilin but lack SMN. Treatment of cells with leptomycin B (LMB) inhibits both the accumulation of snRNPs in nuclear bodies and their subsequent accumulation in speckles. The formation of...
J Cell Sci (2001) 114 (17): 3155–3166.
Published: 01 September 2001
.... The consensus mutant GFP-AnxII(L10A/L12A) confirmed that these residues are necessary for nuclear exclusion. The nuclear exclusion of GFP-AnxII(1-22) was temperature-dependent and reversible, and the nuclear export inhibitor leptomycin B (LmB) caused GFP-AnxII or overexpressed AnxII monomer to...