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Keywords: LPA
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Journal Articles
J Cell Sci (2021) 134 (8): jcs254888.
Published: 22 April 2021
... to lysosomes via the canonical ubiquitin-mediated pathway independently of ALIX and ARRDC3 ( Dores et al., 2012 ; Hasdemir et al., 2007 ). The LPARs and SPR1 also use the canonical ubiquitin-driven lysosomal pathway for degradation ( Rosen et al., 2008 ; Zhao et al., 2016 ). Yet LPA- and S1P-induced Hippo...
Includes: Supplementary data
Journal Articles
J Cell Sci (2017) 130 (20): 3455–3466.
Published: 15 October 2017
...Olivia Susanto; Yvette W. H. Koh; Nick Morrice; Sergey Tumanov; Peter A. Thomason; Matthew Nielson; Luke Tweedy; Andrew J. Muinonen-Martin; Jurre J. Kamphorst; Gillian M. Mackay; Robert H. Insall ABSTRACT Melanoma cells steer out of tumours using self-generated lysophosphatidic acid (LPA) gradients...
Includes: Supplementary data
Journal Articles
J Cell Sci (2016) 129 (20): 3948–3957.
Published: 15 October 2016
...Susanna A. Jethwa; Emma J. Leah; Qifeng Zhang; Nicholas A. Bright; David Oxley; Martin D. Bootman; Simon A. Rudge; Michael J. O. Wakelam ABSTRACT Autotaxin (ATX; also known as ENPP2), the lysophospholipase responsible for generating the lipid receptor agonist lysophosphatidic acid (LPA...
Journal Articles
J Cell Sci (2009) 122 (24): 4558–4569.
Published: 15 December 2009
.... * Author for correspondence ( davisgeo@health.missouri.edu ) 5 10 2009 © The Company of Biologists Limited 2009 2009 MT1-MMP Invasion Cdc42 HT1080 LPA Three-dimensional Nucleus Metastasis Extracellular matrix Tumor cell metastasis and invasion predict poor survival...
Includes: Multimedia, Supplementary data
Journal Articles
In collection:
Lipid Biology
J Cell Sci (2005) 118 (22): 5291–5304.
Published: 15 November 2005
...Nikhil M. Urs; Kymry T. Jones; Paul D. Salo; Jamie E. Severin; JoAnn Trejo; Harish Radhakrishna Lysophosphatidic acid (LPA) stimulates heterotrimeric G protein signaling by activating three closely related receptors, termed LPA 1 , LPA 2 and LPA 3 . Here we show that in addition to promoting LPA 1...
Journal Articles
J Cell Sci (2003) 116 (18): 3835–3846.
Published: 15 September 2003
...Martina Stähle; Christine Veit; Ulla Bachfischer; Karina Schierling; Bettina Skripczynski; Alan Hall; Peter Gierschik; Klaudia Giehl Lysophosphatidic acid (LPA) is a serum-borne phospholipid with hormone and growth factor-like properties. LPA has been shown to modulate tumor cell invasion...