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In collection:Cell Biology and Disease
Aleena K. S. Arakaki, Wen-An Pan, Helen Wedegaertner, Ivette Roca-Mercado, Logan Chinn, Taranjit S. Gujral, JoAnn Trejo
J Cell Sci (2021) 134 (8): jcs254888.
Published: 22 April 2021
... to lysosomes via the canonical ubiquitin-mediated pathway independently of ALIX and ARRDC3 ( Dores et al., 2012 ; Hasdemir et al., 2007 ). The LPARs and SPR1 also use the canonical ubiquitin-driven lysosomal pathway for degradation ( Rosen et al., 2008 ; Zhao et al., 2016 ). Yet LPA- and S1P-induced Hippo...
Includes: Supplementary data
Olivia Susanto, Yvette W. H. Koh, Nick Morrice, Sergey Tumanov, Peter A. Thomason, Matthew Nielson, Luke Tweedy, Andrew J. Muinonen-Martin, Jurre J. Kamphorst, Gillian M. Mackay, Robert H. Insall
J Cell Sci (2017) 130 (20): 3455–3466.
Published: 15 October 2017
...Olivia Susanto; Yvette W. H. Koh; Nick Morrice; Sergey Tumanov; Peter A. Thomason; Matthew Nielson; Luke Tweedy; Andrew J. Muinonen-Martin; Jurre J. Kamphorst; Gillian M. Mackay; Robert H. Insall ABSTRACT Melanoma cells steer out of tumours using self-generated lysophosphatidic acid (LPA) gradients...
Includes: Supplementary data
Susanna A. Jethwa, Emma J. Leah, Qifeng Zhang, Nicholas A. Bright, David Oxley, Martin D. Bootman, Simon A. Rudge, Michael J. O. Wakelam
J Cell Sci (2016) 129 (20): 3948–3957.
Published: 15 October 2016
...Susanna A. Jethwa; Emma J. Leah; Qifeng Zhang; Nicholas A. Bright; David Oxley; Martin D. Bootman; Simon A. Rudge; Michael J. O. Wakelam ABSTRACT Autotaxin (ATX; also known as ENPP2), the lysophospholipase responsible for generating the lipid receptor agonist lysophosphatidic acid (LPA...
Kevin E. Fisher, Anastasia Sacharidou, Amber N. Stratman, Anne M. Mayo, Sarah B. Fisher, Rachel D. Mahan, Michael J. Davis, George E. Davis
J Cell Sci (2009) 122 (24): 4558–4569.
Published: 15 December 2009
.... * Author for correspondence ( firstname.lastname@example.org ) 5 10 2009 © The Company of Biologists Limited 2009 2009 MT1-MMP Invasion Cdc42 HT1080 LPA Three-dimensional Nucleus Metastasis Extracellular matrix Tumor cell metastasis and invasion predict poor survival...
Includes: Multimedia, Supplementary data
In collection:Lipid Biology
J Cell Sci (2005) 118 (22): 5291–5304.
Published: 15 November 2005
...Nikhil M. Urs; Kymry T. Jones; Paul D. Salo; Jamie E. Severin; JoAnn Trejo; Harish Radhakrishna Lysophosphatidic acid (LPA) stimulates heterotrimeric G protein signaling by activating three closely related receptors, termed LPA 1 , LPA 2 and LPA 3 . Here we show that in addition to promoting LPA 1...
Martina Stähle, Christine Veit, Ulla Bachfischer, Karina Schierling, Bettina Skripczynski, Alan Hall, Peter Gierschik, Klaudia Giehl
J Cell Sci (2003) 116 (18): 3835–3846.
Published: 15 September 2003
...Martina Stähle; Christine Veit; Ulla Bachfischer; Karina Schierling; Bettina Skripczynski; Alan Hall; Peter Gierschik; Klaudia Giehl Lysophosphatidic acid (LPA) is a serum-borne phospholipid with hormone and growth factor-like properties. LPA has been shown to modulate tumor cell invasion...