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Keywords: LEF1
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Journal Articles
In collection:
Stem cell biology and organoids
Journal:
Journal of Cell Science
J Cell Sci (2017) 130 (22): 3809–3817.
Published: 15 November 2017
...-inhibiting action. TFCP2L1-mediated suppression of mesoderm and trophectoderm differentiation, however, seems to be due to downregulation of Lef1 expression. Our study thus provides an expanded understanding of the function of TFCP2L1 and the pluripotency regulation network of ESCs. * Author...
Includes: Supplementary data
Journal Articles
Journal:
Journal of Cell Science
J Cell Sci (2007) 120 (9): 1646–1653.
Published: 1 May 2007
... (LEF1), when functionally activated by phosphorylated Smad2 (Smad2- P ) and Smad4 (rather than β-catenin), binds with the promoter of the E-cadherin gene to repress its transcription in response to TGFβ3 signaling. Furthermore, we found that TGFβ3 signaling stimulates epithelial-mesenchymal...
Includes: Supplementary data
