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Keywords: Kindlin-3
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Journal Articles
J Cell Sci (2021) 134 (22): jcs259040.
Published: 26 November 2021
... sealing zones that enable them to adhere to and resorb bone. Sealing zones consist of densely packed podosomes tightly interconnected by actin fibers. Their formation requires the presence of the hematopoietic integrin regulator kindlin-3 (also known as Fermt3). In this study, we investigated osteoclasts...
Includes: Supplementary data
Journal Articles
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Adhesion , Cytoskeleton
J Cell Sci (2021) 134 (8): jcs256115.
Published: 20 April 2021
...-containing kindlin family comprises three members, kindlin-1, kindlin-2 and kindlin-3 (also known as FERMT1, FERMT2 and FERMT3), which share high sequence similarity (identity >50%), as well as domain organization, but exhibit diverse tissue-specific expression patterns and cellular functions. Given...