... disorganisation of the chromosome periphery with alterations in the localisation of Ki-67 (also known as MKI67) and nucleolin (NCL), and the formation of abnormal cytoplasmic aggregates. Furthermore, CCDC86-depleted cells displayed errors in chromosome alignment, altered spindle length and increased apoptosis...

...Nuria Andrés-Sánchez; Daniel Fisher; Liliana Krasinska ABSTRACT What do we know about Ki-67, apart from its usefulness as a cell proliferation biomarker in histopathology? Discovered in 1983, the protein and its regulation of expression and localisation throughout the cell cycle have been well...

...Masatoshi Takagi; Takao Ono; Toyoaki Natsume; Chiyomi Sakamoto; Mitsuyoshi Nakao; Noriko Saitoh; Masato T. Kanemaki; Tatsuya Hirano; Naoko Imamoto ABSTRACT Although condensins play essential roles in mitotic chromosome assembly, Ki-67 (also known as MKI67), a protein localizing to the periphery...

... 2004 Nucleolus TRF2 UBF B23 Ku antigen Cell cycle Ki-67 Telomere The nucleolus is a eukaryotic subnuclear organelle where ribosomal RNAs are transcribed, processed, modified and, finally, assembled into ribosomes. However, there is accumulating evidence pointing to further nucleolar...

...Ian R. Kill ABSTRACT The Ki-67 antigen is detected in proliferating cells in all phases of the cell division cycle. Throughout most of inter-phase, the Ki-67 antigen is localised within the nucleolus. To learn more about the relationship between the Ki-67 antigen and the nucleolus, we have compared...