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Keywords: JNK activityClose
Jacques-Antoine Haefliger, Thomas Tawadros, Laure Meylan, Sabine Le Gurun, Marc-Estienne Roehrich, David Martin, Bernard Thorens, Gérard Waeber
Journal: Journal of Cell Science
J Cell Sci (2003) 116 (8): 1463–1469.
Published: 15 April 2003
... the contribution of IB1/JIP-1 to β-cell survival. Exposure of the insulin-producing cell line INS-1 or isolated rat pancreatic islets to cytokines (interferon-γ, tumor necrosis factor-α and interleukin-1β) induced a marked reduction of IB1/JIP-1 content and a concomitant increase in JNK activity and apoptosis rate...