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Keywords: Iodide uptakeClose
Vicki E. Smith, Martin L. Read, Andrew S. Turnell, Rachel J. Watkins, John C. Watkinson, Greg D. Lewy, Jim C. W. Fong, Sally R. James, Margaret C. Eggo, Kristien Boelaert, Jayne A. Franklyn, Christopher J. McCabe
Journal: Journal of Cell Science
J Cell Sci (2009) 122 (18): 3393–3402.
Published: 15 September 2009
... uptake, impacting on the efficacy of radioiodine ablation therapy. PTTG binding factor (PBF) is a proto-oncogene implicated in the pathogenesis of thyroid cancer. We recently reported that PBF inhibits iodide uptake, and have now elucidated a mechanism by which PBF directly modulates sodium iodide...
Includes: Supplementary data