1-20 of 23
Keywords: Intraflagellar transport
Close
Follow your search
Access your saved searches in your account

Would you like to receive an alert when new items match your search?
Close Modal
Sort by
Journal Articles
J Cell Sci jcs.260303.
Published: 1 December 2022
... that wdr47/nmtn-1 deletion affects movement of intraflagellar transport (IFT) particles and their cargo delivery in AWB neurons. Our results indicate that WDR47/NMTN-1 is essential for AWB neuron ciliary morphology and function, which reveal a novel mechanism for cell-specific ciliogenesis. Since WDR47/NMTN...
Journal Articles
J Cell Sci (2022) 135 (16): jcs260299.
Published: 22 August 2022
... , 1018 - 1021 . 10.1038/nature04117 Desai , P. B. , Stuck , M. W. , Lv , B. and Pazour , G. J. ( 2020 ). Ubiquitin links smoothened to intraflagellar transport to regulate Hedgehog signaling . J. Cell Biol. 219 , e201912104 . 10.1083/jcb.201912104 Deshpande...
Includes: Supplementary data
Journal Articles
In collection:
Cilia and Flagella
J Cell Sci (2023) 136 (5): jcs259257.
Published: 17 May 2022
...Alice Dupont Juhl; Zeinab Anvarian; Stefanie Kuhns; Julia Berges; Jens S. Andersen; Daniel Wüstner; Lotte B. Pedersen ABSTRACT Primary cilia are microtubule-based sensory organelles whose assembly and function rely on the conserved bidirectional intraflagellar transport (IFT) system, which...
Includes: Supplementary data
Journal Articles
In collection:
Cilia and Flagella
J Cell Sci (2021) 134 (3): jcs253492.
Published: 11 February 2021
...Cecile Fort; Peter Collingridge; Colin Brownlee; Glen Wheeler ABSTRACT The movement of ciliary membrane proteins is directed by transient interactions with intraflagellar transport (IFT) trains. The green alga Chlamydomonas has adapted this process for gliding motility, using retrograde IFT motors...
Includes: Supplementary data
Journal Articles
In collection:
Cilia and Flagella
J Cell Sci (2020) 133 (18): jcs248989.
Published: 23 September 2020
... at their distal end via intraflagellar transport (IFT). Immunofluorescence assays, 3D electron microscopy and live-cell imaging revealed that IFT was present in all T. brucei life cycle stages. IFT proteins are concentrated at the base, and IFT trains are located along doublets 3–4 and 7–8 and travel...
Includes: Supplementary data
Journal Articles
J Cell Sci (2020) 133 (6): jcs240614.
Published: 30 March 2020
.... Published by The Company of Biologists Ltd 2020 Summary: We discuss current understanding of the cytoplasmic dynein-2 microtubule motor, and its roles in cilia assembly and function. Dynein-2 Cilia Intraflagellar transport Microtubule motors The cytoplasmic dynein-2 light...
Includes: Supplementary data
Journal Articles
J Cell Sci (2019) 132 (6): jcs229047.
Published: 15 March 2019
... that ubiquitylation of α-tubulin is required for the normal kinetics of axonemal disassembly. Immunoprecipitation and glutathione-S-transferase pulldown assays demonstrated that the retrograde intraflagellar transport (IFT) protein, IFT139, interacted with a variety of ubiquitylated proteins, including α-tubulin...
Includes: Supplementary data
Journal Articles
In collection:
Cilia and Flagella
J Cell Sci (2019) 132 (5): jcs228296.
Published: 22 February 2019
...Diego Huet; Thierry Blisnick; Sylvie Perrot; Philippe Bastin ABSTRACT Intraflagellar transport (IFT), the movement of protein complexes responsible for the assembly of cilia and flagella, is remarkably conserved from protists to humans. However, two IFT components (IFT25 and IFT27) are missing from...
Includes: Supplementary data
Journal Articles
In collection:
Cilia and Flagella
J Cell Sci (2019) 132 (5): jcs222331.
Published: 15 February 2019
... by The Company of Biologists Ltd 2019 http://www.biologists.com/user-licence-1-1/ Highlighted Article:   Bbs4 −/− mice exhibited reduced olfactory sensory neuron cilia length/number and basal body number, as well as miscoordination of intraflagellar transport. Ectopic re-expression of BBS4...
Includes: Supplementary data
Journal Articles
In collection:
Cilia and Flagella
J Cell Sci (2019) 132 (3): jcs220749.
Published: 11 February 2019
...Tyler Picariello; Jason M. Brown; Yuqing Hou; Gregory Swank; Deborah A. Cochran; Oliver D. King; Karl Lechtreck; Gregory J. Pazour; George B. Witman ABSTRACT Intraflagellar transport (IFT), which is essential for the formation and function of cilia in most organisms, is the trafficking of IFT...
Includes: Supplementary data
Journal Articles
In collection:
Cilia and Flagella
J Cell Sci (2017) 130 (9): 1662–1674.
Published: 1 May 2017
...Bo Lv; Lei Wan; Michael Taschner; Xi Cheng; Esben Lorentzen; Kaiyao Huang ABSTRACT Cilia are microtubule-based organelles and perform motile, sensing and signaling functions. The assembly and maintenance of cilia depend on intraflagellar transport (IFT). Besides ciliary localization, most IFT...
Includes: Supplementary data
Journal Articles
In collection:
Cilia and Flagella
J Cell Sci (2016) 129 (15): 3026–3041.
Published: 1 August 2016
...Cécile Fort; Serge Bonnefoy; Linda Kohl; Philippe Bastin ABSTRACT Intraflagellar transport (IFT) is required for construction of most cilia and flagella. Here, we used electron microscopy, immunofluorescence and live video microscopy to show that IFT is absent or arrested in the mature flagellum...
Includes: Supplementary data
Journal Articles
J Cell Sci (2016) 129 (10): 2064–2074.
Published: 15 May 2016
...Elisa Vannuccini; Eugenio Paccagnini; Francesca Cantele; Mariangela Gentile; Daniele Dini; Federica Fino; Dennis Diener; Caterina Mencarelli; Pietro Lupetti ABSTRACT Intraflagellar transport (IFT) is responsible for the bidirectional trafficking of molecular components required for the elongation...
Includes: Supplementary data
Journal Articles
J Cell Sci (2014) 127 (21): 4774–4787.
Published: 1 November 2014
...David Asante; Nicola L. Stevenson; David J. Stephens ABSTRACT Cytoplasmic dynein-2 is the motor for retrograde intraflagellar transport (IFT), and mutations in dynein-2 are known to cause skeletal ciliopathies. Here, we define for the first time the composition of the human cytoplasmic dynein-2...
Includes: Supplementary data
Journal Articles
J Cell Sci (2014) 127 (9): 1924–1937.
Published: 1 May 2014
..., a component of the intraflagellar transport (IFT) system that controls ciliogenesis, as a central regulator of TCR recycling to the immune synapse. Here, we have investigated the interplay of IFT20 with the Rab GTPase network that controls recycling. We found that IFT20 forms a complex with Rab5 and the TCR...
Includes: Supplementary data
Journal Articles
J Cell Sci (2013) 126 (1): 327–338.
Published: 1 January 2013
...Johanna Buisson; Nicolas Chenouard; Thibault Lagache; Thierry Blisnick; Jean-Christophe Olivo-Marin; Philippe Bastin Summary Intraflagellar transport (IFT) is necessary for the construction of cilia and flagella. IFT proteins are concentrated at the base of the flagellum but little is known about...
Includes: Supplementary data
Journal Articles
J Cell Sci (2010) 123 (12): 2035–2044.
Published: 15 June 2010
... Trypanosomatids Intraflagellar transport Myosin Trafficking Myosin proteins constitute a group of actin-based molecular motors that produce movement along the actin filaments and have diverse motile functions in eukaryotic cells, ranging from muscle contraction and pseudopodal motility, to vesicle...
Includes: Multimedia, Supplementary data
Journal Articles
In collection:
Lipid Biology
J Cell Sci (2010) 123 (4): 529–536.
Published: 15 February 2010
... as ciliopathies, result from defective cilium function has expanded interest in these structures. Among the many properties of cilia, motility and intraflagellar transport have been most extensively studied. The latter is the process by which multiprotein complexes associate with microtubule motors to transport...
Journal Articles
J Cell Sci (2009) 122 (6): 834–841.
Published: 15 March 2009
..., we demonstrate that RABL5 colocalises with intraflagellar transport (IFT) proteins at the basal body and in the flagellum matrix of the protist Trypanosoma brucei . RABL5 fused to GFP exhibits anterograde movement in the flagellum of live trypanosomes, suggesting it could be associated with IFT...
Includes: Multimedia, Supplementary data
Journal Articles
J Cell Sci (2008) 121 (22): 3704–3716.
Published: 15 November 2008
.... By analysis of anterograde or retrograde intraflagellar transport in IFT88 RNAi or IFT140 RNAi mutant cells, we show that elongation of the new flagellum is not required for flagellar pocket formation but is essential for its organisation, orientation and function. Transmission electron microscopy revealed...
Includes: Supplementary data