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Keywords: Intercalated disc
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Journal Articles
J Cell Sci (2019) 132 (5): jcs199612.
Published: 18 February 2019
... that are localized to the intercalated disc region, which electromechanically couples adjacent cardiomyocytes. To date, the underlying molecular dysfunctions are not well characterized. In two murine AC models, we find an upregulation of the skeletal muscle actin gene ( Acta1 ), which is known to be a compensatory...
Includes: Supplementary data
Journal Articles
J Cell Sci (2019) 132 (3): jcs221606.
Published: 11 February 2019
...) interactome along the cell–cell contacts of primary cardiomyocytes. CDH2 N-cadherin Cardiomyocyte Adherens junction Intercalated disc Proteomics Interactome Heart function requires mechanical coupling and chemical communication between cardiomyocytes through a specialized adhesive...
Includes: Supplementary data
Journal Articles
J Cell Sci (2007) 120 (12): 2126–2136.
Published: 15 June 2007
... is expressed predominantly in cardiomyocytes, where it colocalizes with αE-catenin at the intercalated discs. Whether αT- and αE-catenin have specific or synergistic functions remains unknown. In this study we used the yeast two-hybrid approach to identify specific functions of αT-catenin. An interaction...