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Keywords: Integrin signaling
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Journal Articles
Journal:
Journal of Cell Science
J Cell Sci (2019) 132 (10): jcs224030.
Published: 15 May 2019
...-49217 Clathrin Cell spreading Focal adhesions Integrin signaling Summary: The highly conserved clathrin light chain A, whose function has been elusive, promotes integrin-mediated signaling, association of clathrin with the WAVE complex, and efficient cell spreading and migration...
Includes: Supplementary data
Journal Articles
Benjamin Richier, Yoshiko Inoue, Ulrich Dobramysl, Jonathan Friedlander, Nicholas H. Brown, Jennifer L. Gallop
Journal:
Journal of Cell Science
J Cell Sci (2018) 131 (16): jcs217133.
Published: 16 August 2018
... occurs as a result of integrin signaling. Loss of the integrin subunits αPS2 and βPS (also known as If and Mys, respectively, in flies) increased filopodia number and length at stages when they are normally suppressed. Conversely, inducing integrin signaling, achieved by the expression of constitutively...
Includes: Supplementary data
Journal Articles
Journal:
Journal of Cell Science
J Cell Sci (2015) 128 (23): 4273–4278.
Published: 1 December 2015
... expansion of T lymphocytes and potentially of other normal and transformed cells. CD98 Clonal expansion Immunobiology Integrin signaling In vertebrates, adaptive immunity provides for protection against a remarkably diverse collection of pathogens. During an adaptive immune response, a few...
Journal Articles
Journal:
Journal of Cell Science
J Cell Sci (2015) 128 (10): 1961–1968.
Published: 15 May 2015
..., the onset of contractility and extent to which force-mediated integrin signaling regulates fate choices is not understood. To address the requirement of tractions forces for differentiation, we examined mouse embryonic stem cell (ESC) specification towards definitive endoderm on fibrillar fibronectin...
Includes: Supplementary data
Journal Articles
Journal:
Journal of Cell Science
J Cell Sci (2014) 127 (5): 1117–1127.
Published: 1 March 2014
... detyrosinated microtubules in NIH3T3 cells and this function resulted from the activation of a RhoA-dependent microtubule stabilization pathway regulated by integrin signaling and the formin mDia1. Induction of microtubule stability by Aβ was also initiated by dimerization of APP and required caspase activity...
Includes: Supplementary data
Journal Articles
Journal:
Journal of Cell Science
J Cell Sci (2013) 126 (24): 5735–5747.
Published: 15 December 2013
... that allows relaxation of the α1/α1′-helix in the resting state and transmission of bidirectional conformational signals by helix unbending upon integrin activation. Integrin activation α1/α1′-helix Integrin signaling The cell spreading assay and immunostaining was as described before ( Zhu et al...
Includes: Supplementary data
Journal Articles
Ori Maller, Kirk C. Hansen, Traci R. Lyons, Irene Acerbi, Valerie M. Weaver, Rytis Prekeris, Aik-Choon Tan, Pepper Schedin
Journal:
Journal of Cell Science
J Cell Sci (2013) 126 (18): 4108–4110.
Published: 15 September 2013
... protection ( Schedin et al., 2004 ). E-cadherin Collagen organization Integrin signaling Tumor-suppressive extracellular matrix ECM © 2013. Published by The Company of Biologists Ltd 2013 3 06 2013 * Author for correspondence ( [email protected] ) ...
Includes: Supplementary data
Journal Articles
Journal:
Journal of Cell Science
J Cell Sci (2007) 120 (1): 66–76.
Published: 1 January 2007
... release ( Fig. 3C ), corresponding with the morphological recovery observed ( Fig. 2H,J ; indicated by R). In conclusion, these data suggest that both integrin signaling and growth factor signaling in early G1 phase depend on integrity of the actin cytoskeleton. Fig. 2. CCD and LB reversibly...
Journal Articles
Journal:
Journal of Cell Science
J Cell Sci (2006) 119 (7): 1233–1243.
Published: 1 April 2006
... reticulum Integrin signaling Microtubules Protein tyrosine phosphatase 1B (PTP1B) is targeted to the cytosolic face of the membranes of the endoplasmic reticulum (ER) via a hydrophobic sequence at its C terminus ( Frangioni et al., 1992 ). As the catalytic domain faces the cytosol, ER bound enzyme...
Includes: Multimedia, Supplementary data
Journal Articles
Patrick W. Suen, Dusko Ilic, Elena Caveggion, Giorgio Berton, Caroline H. Damsky, Clifford A. Lowell
Journal:
Journal of Cell Science
J Cell Sci (1999) 112 (22): 4067–4078.
Published: 15 November 1999
.... This signaling pathway is critically dependent on tyrosine kinases. To investigate the role of the Src-family of tyrosine kinases in integrin signal transduction, we have examined the adhesive properties of macrophages isolated from hck ‐/‐ fgr ‐/‐ double knockout mice which lack two of the three predominant Src...