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1-9 of 9
Keywords: Integrin activation
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Journal Articles
In collection:
Adhesion
Fangyuan Zhou, Fang Zhang, Veronika I. Zarnitsyna, Larissa Doudy, Zhou Yuan, Kaitao Li, Rodger P. McEver, Hang Lu, Cheng Zhu
Journal:
Journal of Cell Science
J Cell Sci (2021) 134 (18): jcs258046.
Published: 23 September 2021
... is required for β 2 integrin activation, which is consistent with previous studies (Fan and Ley, 2015 ; Zarbock et al., 2007). Furthermore, the anti-E-selectin mAb ES1 (Fab) totally abolished adhesion (Fig. 2 C), confirming that E-selectin binding is required for β 2 integrins in Ca 2+ /Mg 2+ to interact...
Includes: Supplementary data
Journal Articles
In collection:
Adhesion
Jiyoon Kim, Chansik Yang, Eun Jin Kim, Jungim Jang, Se-Jong Kim, So Min Kang, Moon Gyo Kim, Hosung Jung, Dongeun Park, Chungho Kim
Journal:
Journal of Cell Science
J Cell Sci (2016) 129 (10): 2030–2042.
Published: 15 May 2016
... filaments underneath the plasma membrane might provide integrin-binding sites to mediate integrin clustering, which in turn can enhance integrin–ligand interaction. Integrin Vimentin Integrin activation H-Ras Talin National Research Foundation of Korea (NRF) and funded by the Ministry...
Includes: Supplementary data
Journal Articles
Journal:
Journal of Cell Science
J Cell Sci (2015) 128 (23): 4341–4352.
Published: 1 December 2015
...-70-like adaptor of T cells (SLAT). SLAT Def6 Rap1 Integrin activation T cell-adhesion Inside-out signaling Immunological synapse An efficient adaptive immune response depends on the capacity of leukocytes, especially T cells, to quickly recirculate through blood and lymph...
Includes: Supplementary data
Journal Articles
Clotilde Huet-Calderwood, Nina N. Brahme, Nikit Kumar, Amy L. Stiegler, Srikala Raghavan, Titus J. Boggon, David A. Calderwood
Journal:
Journal of Cell Science
J Cell Sci (2014) 127 (19): 4308–4321.
Published: 1 October 2014
...Clotilde Huet-Calderwood; Nina N. Brahme; Nikit Kumar; Amy L. Stiegler; Srikala Raghavan; Titus J. Boggon; David A. Calderwood ABSTRACT Kindlins are essential FERM-domain-containing focal adhesion (FA) proteins required for proper integrin activation and signaling. Despite the widely accepted...
Includes: Supplementary data
Journal Articles
Journal:
Journal of Cell Science
J Cell Sci (2013) 126 (24): 5735–5747.
Published: 15 December 2013
... that allows relaxation of the α1/α1′-helix in the resting state and transmission of bidirectional conformational signals by helix unbending upon integrin activation. * Present address: College of Animal Science and Veterinary Medicine, Qingdao Agricultural University, Qingdao 266109, China...
Includes: Supplementary data
Journal Articles
Mohamed Bouaouina, Klodiana Jani, Jenny Y. Long, Stefan Czerniecki, Elizabeth M. Morse, Stephanie J. Ellis, Guy Tanentzapf, Frieder Schöck, David A. Calderwood
Journal:
Journal of Cell Science
J Cell Sci (2012) 125 (23): 5647–5657.
Published: 1 December 2012
... of the scaffold protein, talin, to the cytoplasmic tail of β-integrin causes a conformational change of the extracellular domains of the integrin heterodimer, thus allowing high-affinity binding of ECM ligands. This essential process is called integrin activation. Here we report that the Z-band alternatively...
Includes: Supplementary data
Journal Articles
Journal:
Journal of Cell Science
J Cell Sci (2008) 121 (3): 265–271.
Published: 1 February 2008
..., respectively. An adaptation of the assay revealed the agonistic activity of these small molecules, thus demonstrating that these compounds may induce secondary effects in vivo via integrin activation. This study provides insight into the dependence of the activity of small molecule anti-integrin compounds upon...
Includes: Supplementary data
Journal Articles
Positive regulation of cell-cell and cell-substrate adhesion by protein kinase A
Available to Purchase
Journal:
Journal of Cell Science
J Cell Sci (2001) 114 (18): 3265–3272.
Published: 15 September 2001
... 1 integrins, and that this enzyme may be required for upregulation of cell-substrate and cell-cell adhesion. *Author for correspondence (e-mail: [email protected]) 1 6 2001 © The Company of Biologists Limited 2001 2001 Integrin activation Cell-cell adhesion cAMP PKA F...
Journal Articles
Superactivation of integrin αvβ3 by low antagonist concentrations
Available to Purchase
Journal:
Journal of Cell Science
J Cell Sci (2001) 114 (8): 1545–1553.
Published: 15 April 2001
...) * Both authors contributed equally to this work 24 01 2001 © 2001 by Company of Biologists 2001 Integrin αvβ3 Vitronectin receptor Affinity modulation Integrin activation Soluble recombinant cell adhesion molecule Cyclo-RGD Integrins are a family of αβ-heterodimeric...