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Keywords: Integrin activation
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Adhesion
J Cell Sci (2021) 134 (18): jcs258046.
Published: 23 September 2021
... was evaluated by dose-response analysis, providing new insight into the signaling mechanism. Leukocyte adhesion Integrin activation Selectin Micropipette adhesion frequency assay Microfluidics National Institutes of Health http://dx.doi.org/10.13039/100000002 R01HL18671 U01CA214354...
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Journal Articles
In collection:
Adhesion
J Cell Sci (2016) 129 (10): 2030–2042.
Published: 15 May 2016
... filaments underneath the plasma membrane might provide integrin-binding sites to mediate integrin clustering, which in turn can enhance integrin–ligand interaction. Integrin Vimentin Integrin activation H-Ras Talin National Research Foundation of Korea (NRF) and funded by the Ministry...
Includes: Supplementary data
Journal Articles
J Cell Sci (2015) 128 (23): 4341–4352.
Published: 1 December 2015
... activation, involving SWAP-70-like adaptor of T cells (SLAT). SLAT Def6 Rap1 Integrin activation T cell-adhesion Inside-out signaling Immunological synapse An efficient adaptive immune response depends on the capacity of leukocytes, especially T cells, to quickly recirculate through blood...
Includes: Supplementary data
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Journal Articles
J Cell Sci (2013) 126 (24): 5735–5747.
Published: 15 December 2013
... that allows relaxation of the α1/α1′-helix in the resting state and transmission of bidirectional conformational signals by helix unbending upon integrin activation. Generation of CHO-k1 or HEK293 cells stably expressing αIIbβ3 constructs was as described before ( Zhu et al., 2007b ). Integrin-expressing...
Includes: Supplementary data
Journal Articles
J Cell Sci (2012) 125 (23): 5647–5657.
Published: 1 December 2012
... of the scaffold protein, talin, to the cytoplasmic tail of β-integrin causes a conformational change of the extracellular domains of the integrin heterodimer, thus allowing high-affinity binding of ECM ligands. This essential process is called integrin activation. Here we report that the Z-band alternatively...
Includes: Supplementary data
Journal Articles
J Cell Sci (2008) 121 (3): 265–271.
Published: 1 February 2008
..., respectively. An adaptation of the assay revealed the agonistic activity of these small molecules, thus demonstrating that these compounds may induce secondary effects in vivo via integrin activation. This study provides insight into the dependence of the activity of small molecule anti-integrin compounds upon...
Includes: Supplementary data
Journal Articles
J Cell Sci (2001) 114 (18): 3265–3272.
Published: 15 September 2001
... ; Danen et al., 1998 ; Giancotti and Ruoslahti, 1999 ; Schoenwaelder and Burridge, 1999 ). *Author for correspondence (e-mail: [email protected] ) 1 6 2001 © The Company of Biologists Limited 2001 2001 Integrin activation Cell-cell adhesion cAMP PKA F-actin Signal...
Journal Articles
J Cell Sci (2001) 114 (8): 1545–1553.
Published: 15 April 2001
... ) * Both authors contributed equally to this work 24 01 2001 © 2001 by Company of Biologists 2001 Integrin αvβ3 Vitronectin receptor Affinity modulation Integrin activation Soluble recombinant cell adhesion molecule Cyclo-RGD Integrins are a family of αβ-heterodimeric...