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Keywords: Insulin resistance
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Journal Articles
J Cell Sci (2022) 135 (1): jcs258584.
Published: 10 January 2022
... mice did not show whole-body insulin resistance. The impaired action of insulin, such as the insensitivity of insulin signalling in adipose tissues, reduces the synthesis of triacylglycerol and increases lipolysis. Indeed, we have previously reported that PRIP-KO mice have a lean phenotype...
Includes: Supplementary data
Journal Articles
Journal Articles
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Lipid biology
J Cell Sci (2009) 122 (12): 1970–1978.
Published: 15 June 2009
... differentiation, insulin resistance, lipid storage and obesity, but the underlying cellular defects caused by altering lipin levels are not known. Here, we identify the Caenorhabditis elegans lipin homolog (LPIN-1) and examine its affect on NE dynamics. We find that downregulating LPIN-1 by RNAi results...
Includes: Multimedia, Supplementary data