... remains to be characterized ( Slot et al., 1991a ; Ploug et al., 1998 ; Martin et al., 1999 ). Understanding the basis for the exclusion of GLUT4 from the cell surface of basal cells and sequestration in intracellular storage compartments is fundamental to understanding insulin action. Although...

.... * Author for correspondence (e-mail: [email protected] ) 31 10 2000 7 09 2000 © 2000 by Company of Biologists 2000 Insulin action Trafficking GLUT4 An important component of whole body glucose homeostasis is the increased glucose uptake by adipose and muscle...

[email protected] ) 10 02 1996 10 07 1997 © 1997 by Company of Biologists 1997 Insulin action Protein targeting Insulin stimulates glucose transport in adipose tissue and muscle through the translocation of a glucose transporter isoform, GLUT4, from an intracellular site...