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1-8 of 8
Keywords: Inositol 1,4,5-trisphosphate
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Journal Articles
In collection:
Metabolism
Ariel Contreras-Ferrat, Paola Llanos, César Vásquez, Alejandra Espinosa, César Osorio-Fuentealba, Manuel Arias-Calderon, Sergio Lavandero, Amira Klip, Cecilia Hidalgo, Enrique Jaimovich
Journal:
Journal of Cell Science
J Cell Sci (2014) 127 (9): 1911–1923.
Published: 1 May 2014
... production. A ryanodine receptor (RyR) channel agonist stimulated GLUT4myc translocation and insulin stimulated RyR1-mediated Ca 2+ release by promoting RyR1 S -glutathionylation. This pathway acts in parallel to insulin-mediated stimulation of inositol-1,4,5-trisphosphate (IP 3)-activated Ca 2+ channels...
Includes: Supplementary data
Journal Articles
Journal:
Journal of Cell Science
J Cell Sci (2014) 127 (7): 1607–1619.
Published: 1 April 2014
... from the endoplasmic reticulum (ER) intracellular Ca 2+ stores is enhanced by loss of K-Ras G13D through an increase in the Ca 2+ content of the ER store and a modification of the abundance of inositol 1,4,5-trisphosphate (IP 3) receptor (IP3R) subtypes. Consistently, uptake of Ca 2+ into mitochondria...
Includes: Supplementary data
Journal Articles
Journal:
Journal of Cell Science
J Cell Sci (2006) 119 (17): 3705–3717.
Published: 1 September 2006
... for Ca 2+ signaling, although the molecular identity of the channels responsible for the Ca 2+ signals remains largely unknown. We have cloned - for the first time in a protozoan - the full sequence of the gene encoding a putative inositol (1,4,5)-trisphosphate (Ins(1,4,5) P 3) receptor from Paramecium...
Includes: Multimedia, Supplementary data
Journal Articles
Andrew Proven, H. Llewelyn Roderick, Stuart J. Conway, Michael J. Berridge, Jeffrey K. Horton, Stephen J. Capper, Martin D. Bootman
Journal:
Journal of Cell Science
J Cell Sci (2006) 119 (16): 3363–3375.
Published: 15 August 2006
...Andrew Proven; H. Llewelyn Roderick; Stuart J. Conway; Michael J. Berridge; Jeffrey K. Horton; Stephen J. Capper; Martin D. Bootman Although ventricular cardiomyocytes express inositol 1,4,5-trisphosphate [Ins(1,4,5) P 3 ] receptors, it is unclear how these Ca 2+ channels contribute to the effects...
Includes: Supplementary data
Journal Articles
Calcium puffs are generic InsP 3 -activated elementary calcium signals and are downregulated by prolonged hormonal stimulation to inhibit cellular calcium responses
Available to PurchaseStephen C. Tovey, Patrick de Smet, Peter Lipp, David Thomas, Kenneth W. Young, Ludwig Missiaen, Humbert De Smedt, Jan B. Parys, Michael J. Berridge, Jan Thuring, Andrew Holmes, Martin D. Bootman
Journal:
Journal of Cell Science
J Cell Sci (2001) 114 (22): 3979–3989.
Published: 15 November 2001
...-trisphosphate receptors, are building blocks for local and global Ca 2+ signalling. We characterized Ca 2+ puffs in six cell types that expressed differing ratios of the three inositol 1,4,5-trisphosphate receptor isoforms. The amplitudes, spatial spreads and kinetics of the events were similar in each...
Journal Articles
Sustained elevation in inositol 1,4,5-trisphosphate results in inhibition of phosphatidylinositol transfer protein activity and chronic depletion of the agonist-sensitive phosphoinositide pool
Available to Purchase
Journal:
Journal of Cell Science
J Cell Sci (2000) 113 (14): 2631–2638.
Published: 15 July 2000
...Caroline J. Speed; Christina A. Mitchell ABSTRACT The 43 kDa inositol polyphosphate 5-phosphatase (5-phosphatase) hydrolyses the signalling molecules inositol 1,4,5-trisphosphate (Ins(1,4,5)P 3) and inositol 1,3,4,5-tetrakisphosphate (Ins(1,3,4,5)P 4) in a signal-terminating reaction. We have...
Journal Articles
Underexpression of the 43 kDa inositol polyphosphate 5-phosphatase is associated with spontaneous calcium oscillations and enhanced calcium responses following endothelin-1 stimulation
Available to Purchase
Journal:
Journal of Cell Science
J Cell Sci (1999) 112 (5): 669–679.
Published: 1 March 1999
...Caroline J. Speed; Craig B. Neylon; Peter J. Little; Christina A. Mitchell ABSTRACT The 43 kDa inositol polyphosphate 5-phosphatase (5-phosphatase) hydrolyses the signalling molecules inositol 1,4,5-trisphosphate (Ins(1,4,5)P 3) and inositol 1,3,4,5tetrakisphosphate (Ins(1,3,4,5)P 4) and thereby...
Journal Articles
Inositol 1,4,5-trisphosphate and calcium stimulate actin polymerization in Dictyostelium discoideum
Available to Purchase
Journal:
Journal of Cell Science
J Cell Sci (1986) 82 (1): 41–51.
Published: 1 June 1986
... of actin associated with the cytoskeleton, an event correlated with pseudopodium formation, which ocurrs within 3—5 s of chemotactic receptor stimulation. We report that this response can be mimicked by addition of 5 μM-inositol 1,4,5-trisphosphate (IP 3) or by addition of 100μM-Ca 2+ to saponin...
