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Keywords: Inclusion body
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Journal Articles
In collection:
Proteostasis
J Cell Sci (2021) 134 (7): jcs254201.
Published: 15 April 2021
... that p97 mediates aggresome formation and clearance, and identify a novel role for the adaptor UBXN1 in the process of aggresome formation. UBXN1 is recruited to aggresomes, and UBXN1-knockout cells are unable to form aggresomes. Loss of p97–UBXN1 results in increased Huntingtin polyQ inclusion bodies both...
Includes: Supplementary data
Journal Articles
J Cell Sci (1997) 110 (12): 1403–1411.
Published: 15 June 1997
... depleted tissues showed that mitochondrial intermembrane inclusion bodies appeared in all skeletal muscles analysed, after 11 weeks of feeding. Heart had relatively few even after 18 weeks of analogue feeding and none were evident in kidney, brain or liver. These structures were strongly immuno-positive...