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Keywords: Inclusion body
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Proteostasis
J Cell Sci (2021) 134 (7): jcs254201.
Published: 15 April 2021
... that p97 mediates aggresome formation and clearance, and identify a novel role for the adaptor UBXN1 in the process of aggresome formation. UBXN1 is recruited to aggresomes, and UBXN1-knockout cells are unable to form aggresomes. Loss of p97–UBXN1 results in increased Huntingtin polyQ inclusion bodies both...
Includes: Supplementary data
Journal Articles