...-interactions between SynCAM1 and SynCAM2. Indeed, as we show here, the presence of homophilic and heterophilic cis-interactions modulates the interaction of SynCAMs with trans-binding partners, as observed previously for other immunoglobulin superfamily cell adhesion molecules. These in vitro findings...

... horseshoe arrangement in a number of other cell surface receptors, nearly all of which function in the nervous system. The N-terminal horseshoe appears to be evolutionally selected as a platform for neural receptors. Axon guidance cue Crystal structure Genome-wide search Immunoglobulin superfamily...

... immunoglobulin superfamily members such as CDO, BOC and neogenin. Genetic evidence for the promyogenic roles of some of these factors is emerging. In other cases, potential compensatory or redundant functions necessitate future construction of double or triple mutants. Mechanistic studies in vitro indicate...

... interface leading to localization at cell-cell borders. * Author for correspondence (e-mail: albelda@mail.med.upenn.edu ) 13 02 2000 21 03 2000 © 2000 by Company of Biologists 2000 Cell adhesion molecule Endothelium Cell-cell junction Immunoglobulin superfamily Cell...

... and their tissue-specific expression suggest an important role for these intracytoplasmic domains in IAP function. * Author for correspondence 14 03 1995 07 08 1995 © 1995 by Company of Biologists 1995 integrin alternative splicing immunoglobulin superfamily protein expression...

... interdomain segment. * Author for correspondence 31 03 1995 14 06 1995 © 1995 by Company of Biologists 1995 titin cDNA sequence Type-II domain immunoglobulin superfamily phosphorylation Titin, also known as connectin, is an exceptionally large single chain protein...